EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4v7v
Crystal structure of the E. coli ribosome bound to clindamycin. Deposited 2010-08-16 X-RAY DIFFRACTION resol 3.2891 Å
7028 C3'-endo RNA residues with 191 outliers ( 2.72 % ) from Eta-Theta plot
717 C2'-endo RNA residues with 96 outliers ( 13.39 % ) from Eta-Theta plot
7028 C3'-endo RNA residues with 173 outliers ( 2.46 % ) from Eta'-Theta' plot
717 C2'-endo RNA residues with 95 outliers ( 13.25 % ) from Eta'-Theta' plot
7028 C3'-endo RNA residues with 143 outliers ( 2.03 % ) from Eta"-Theta" plot
717 C2'-endo RNA residues with 46 outliers ( 6.42 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AA | U | 4 | 234.6 | 113.7 | --- | --- | --- | --- | C3'endo | 0.15 |
| 1 | AA | U | 5 | 2.7 | 112.8 | 25.2 | 93.1 | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 64 | 236.7 | 113.9 | 232.4 | 82.3 | --- | --- | C3'endo | 0.184 |
| 1 | AA | G | 94 | 263.1 | 138.3 | 260.1 | 103.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 119 | 226.0 | 68.3 | 232.7 | 73.4 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 210 | 235.4 | 125.7 | 253.9 | 93.2 | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 211 | 91.3 | 261.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | G | 266 | 4.0 | 100.5 | 340.3 | 86.8 | 319.4 | 42.4 | C3'endo | 0.0 |
| 1 | AA | A | 353 | 5.7 | 123.8 | 2.6 | 114.7 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 421 | 124.9 | 308.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 495 | 253.4 | 96.9 | 235.9 | 81.9 | --- | --- | C3'endo | 0.062 |
| 1 | AA | U | 508 | 82.5 | 124.5 | 111.6 | 138.4 | 124.1 | 128.1 | C3'endo | 0.0 |
| 1 | AA | C | 841 | 94.4 | 300.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 842 | 326.2 | 294.7 | 20.0 | 280.4 | --- | --- | C3'endo | 0.294 |
| 1 | AA | A | 845 | 111.1 | 315.8 | 126.1 | 319.3 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1030 | 84.6 | 21.4 | 52.4 | 27.3 | 7.3 | 26.0 | C3'endo | 0.0 |
| 1 | AA | U | 1049 | 14.9 | 90.6 | 15.3 | 60.1 | 13.1 | 22.3 | C3'endo | 0.113 |
| 1 | AA | C | 1136 | 111.4 | 317.8 | 107.6 | 301.5 | --- | --- | C3'endo | 0.122 |
| 1 | AA | A | 1145 | 218.8 | 84.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1168 | 331.1 | 321.1 | 75.6 | 297.9 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 1212 | 301.5 | 87.6 | 297.4 | 60.1 | 148.7 | 25.2 | C3'endo | 0.0 |
| 1 | AA | A | 1285 | 25.5 | 162.6 | 103.2 | 93.4 | 103.8 | 31.7 | C3'endo | 0.0 |
| 1 | AA | A | 1398 | 132.1 | 58.7 | 149.9 | 87.3 | --- | --- | C3'endo | 0.0 |
| 1 | AA | C | 1533 | 5.2 | 280.5 | --- | --- | --- | --- | C3'endo | 0.759 |
| 1 | BA | G | 248 | 122.0 | 311.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 277 | 230.5 | 64.3 | 223.9 | 65.8 | --- | --- | C3'endo | 0.01 |
| 1 | BA | A | 443 | 275.5 | 93.5 | 313.7 | 70.4 | 2.8 | 25.5 | C3'endo | 0.0 |
| 1 | BA | A | 480 | 109.8 | 306.9 | 89.8 | 289.2 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 526 | 213.9 | 101.6 | --- | --- | --- | --- | C3'endo | 0.276 |
| 1 | BA | U | 546 | 313.7 | 118.8 | 312.1 | 134.9 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 613 | 109.4 | 296.3 | 95.8 | 295.8 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 646 | 113.3 | 286.4 | 125.7 | 295.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 846 | 302.7 | 92.8 | 321.4 | 99.9 | 306.3 | 94.7 | C3'endo | 0.0 |
| 1 | BA | U | 931 | 336.1 | 319.2 | 11.2 | 270.7 | 348.9 | 58.2 | C3'endo | 0.519 |
| 1 | BA | U | 1065 | 204.8 | 294.6 | 145.5 | 289.9 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1066 | 226.2 | 298.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1070 | 70.4 | 62.6 | 62.9 | 88.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1088 | 277.9 | 58.5 | 287.8 | 63.6 | 288.0 | 56.8 | C3'endo | 0.0 |
| 1 | BA | G | 1136 | 11.3 | 170.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1141 | 226.4 | 88.7 | 237.4 | 84.0 | --- | --- | C3'endo | 0.804 |
| 1 | BA | C | 1493 | 262.1 | 280.2 | 273.6 | 277.6 | --- | --- | C3'endo | 0.159 |
| 1 | BA | A | 1508 | 228.8 | 87.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1535 | 78.1 | 347.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1584 | 346.0 | 302.0 | 359.1 | 292.0 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1729 | 101.1 | 325.3 | 92.2 | 297.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 1757 | 343.7 | 333.4 | 347.1 | 313.6 | --- | --- | C3'endo | 0.303 |
| 1 | BA | A | 1847 | 53.3 | 285.8 | --- | --- | --- | --- | C3'endo | 0.098 |
| 1 | BA | A | 1969 | 216.2 | 81.5 | --- | --- | --- | --- | C3'endo | 0.059 |
| 1 | BA | A | 1981 | 301.8 | 283.5 | --- | --- | --- | --- | C3'endo | 0.094 |
| 1 | BA | C | 2055 | 237.5 | 44.5 | 255.5 | 56.2 | 311.2 | 133.4 | C3'endo | 0.0 |
| 1 | BA | C | 2143 | 134.4 | 299.7 | 120.8 | 307.9 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2144 | 201.9 | 347.1 | 246.2 | 324.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | C | 2146 | 356.4 | 125.1 | 37.2 | 116.3 | 36.2 | 160.8 | C3'endo | 0.0 |
| 1 | BA | U | 2203 | 54.7 | 101.1 | 53.6 | 75.2 | 76.0 | 339.5 | C3'endo | 0.0 |
| 1 | BA | U | 2402 | 243.5 | 131.9 | 266.5 | 116.6 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 2423 | 331.7 | 91.4 | 337.0 | 69.5 | 311.5 | 48.1 | C3'endo | 0.0 |
| 1 | BA | G | 2502 | 355.3 | 46.3 | 3.7 | 42.8 | 122.4 | 64.5 | C3'endo | 0.0 |
| 1 | BA | G | 2505 | 320.2 | 142.2 | 334.6 | 138.2 | --- | --- | C3'endo | 0.0 |
| 1 | BA | G | 2578 | 46.4 | 125.1 | 67.0 | 151.9 | --- | --- | C3'endo | 0.201 |
| 1 | BA | A | 2820 | 71.2 | 348.5 | 58.9 | 333.0 | 50.6 | 343.2 | C3'endo | 0.0 |
| 1 | BB | A | 66 | 244.5 | 134.9 | 246.2 | 125.9 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 30 | 217.5 | 294.5 | --- | --- | --- | --- | C3'endo | 0.798 |
| 1 | CA | A | 250 | 211.0 | 113.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 251 | 268.1 | 88.1 | 240.2 | 76.5 | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 266 | 353.2 | 93.1 | 339.6 | 86.8 | 329.2 | 47.6 | C3'endo | 0.0 |
| 1 | CA | G | 351 | 212.6 | 103.3 | 226.5 | 126.4 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 353 | 14.4 | 125.1 | 7.6 | 126.0 | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 388 | 326.3 | 89.6 | 343.6 | 42.8 | 262.3 | 34.1 | C3'endo | 0.408 |
| 1 | CA | U | 467 | 269.2 | 294.4 | 285.9 | 287.6 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 723 | 46.4 | 26.1 | 58.4 | 342.9 | 93.4 | 336.4 | C3'endo | 0.0 |
| 1 | CA | C | 841 | 92.5 | 283.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 842 | 329.0 | 299.2 | 27.8 | 290.1 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 843 | 291.8 | 308.9 | 317.9 | 310.3 | 338.2 | 323.5 | C3'endo | 0.0 |
| 1 | CA | A | 845 | 90.1 | 326.4 | 83.1 | 316.7 | --- | --- | C3'endo | 0.0 |
| 1 | CA | C | 934 | 344.2 | 117.4 | 334.1 | 101.3 | 311.1 | 71.1 | C3'endo | 0.0 |
| 1 | CA | A | 974 | 75.8 | 65.4 | 107.7 | 56.3 | 131.2 | 335.5 | C3'endo | 0.0 |
| 1 | CA | U | 982 | 81.9 | 102.5 | 121.7 | 91.1 | 100.7 | 54.2 | C3'endo | 0.0 |
| 1 | CA | U | 992 | 303.2 | 88.2 | 279.4 | 69.8 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1030 | 83.8 | 66.8 | 94.9 | 55.8 | 154.8 | 55.4 | C3'endo | 0.0 |
| 1 | CA | U | 1049 | 350.1 | 99.1 | 359.8 | 62.5 | 63.2 | 11.5 | C3'endo | 0.0 |
| 1 | CA | C | 1054 | 5.7 | 129.5 | 350.6 | 127.9 | 357.2 | 81.2 | C3'endo | 0.0 |
| 1 | CA | U | 1085 | 76.0 | 286.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | G | 1094 | 17.8 | 69.3 | 8.3 | 65.4 | 353.5 | 55.5 | C3'endo | 0.0 |
| 1 | CA | G | 1124 | 225.3 | 115.4 | --- | --- | --- | --- | C3'endo | 0.01 |
| 1 | CA | C | 1136 | 307.1 | 351.8 | 38.7 | 338.9 | 74.2 | 5.4 | C3'endo | 0.0 |
| 1 | CA | G | 1138 | 105.9 | 320.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1145 | 219.7 | 112.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1167 | 0.5 | 31.3 | 60.1 | 279.8 | 46.6 | 157.2 | C3'endo | 0.14 |
| 1 | CA | C | 1200 | 217.1 | 72.5 | 227.8 | 35.3 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1224 | 120.3 | 300.7 | 142.9 | 310.7 | 151.6 | 4.3 | C3'endo | 0.0 |
| 1 | CA | U | 1240 | 38.5 | 325.7 | 34.6 | 331.3 | 76.7 | 346.1 | C3'endo | 0.0 |
| 1 | CA | A | 1256 | 260.7 | 105.7 | 240.8 | 92.2 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1257 | 330.0 | 13.6 | 340.8 | 348.8 | 130.7 | 354.1 | C3'endo | 0.0 |
| 1 | CA | G | 1278 | 231.1 | 62.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1298 | 217.4 | 79.7 | --- | --- | --- | --- | C3'endo | 0.063 |
| 1 | CA | U | 1345 | 243.7 | 108.2 | 231.6 | 115.5 | --- | --- | C3'endo | 0.038 |
| 1 | CA | U | 1380 | 226.6 | 130.9 | --- | --- | --- | --- | C3'endo | 0.08 |
| 1 | CA | A | 1447 | 207.6 | 281.4 | 219.1 | 286.1 | --- | --- | C3'endo | 0.0 |
| 1 | CA | U | 1451 | 106.8 | 322.2 | 104.0 | 300.5 | --- | --- | C3'endo | 0.065 |
| 1 | CA | A | 1493 | 267.7 | 33.6 | 354.4 | 356.3 | 75.6 | 358.0 | C3'endo | 0.0 |
| 1 | DA | A | 91 | 62.0 | 126.2 | 100.7 | 106.9 | 65.7 | 105.8 | C3'endo | 0.0 |
| 1 | DA | A | 241 | 92.3 | 120.6 | 116.1 | 135.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 248 | 124.8 | 298.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 249 | 244.0 | 73.9 | 258.6 | 66.8 | 291.4 | 53.9 | C3'endo | 0.0 |
| 1 | DA | G | 277 | 217.1 | 73.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 301 | 123.3 | 125.7 | 106.3 | 135.2 | 85.2 | 128.9 | C3'endo | 0.0 |
| 1 | DA | A | 311 | 88.0 | 292.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 329 | 305.6 | 298.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 384 | 327.3 | 278.4 | --- | --- | --- | --- | C3'endo | 0.513 |
| 1 | DA | C | 527 | 289.1 | 98.1 | 254.4 | 112.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 546 | 304.1 | 113.4 | 320.1 | 138.9 | 319.8 | 184.0 | C3'endo | 0.0 |
| 1 | DA | A | 547 | 209.3 | 309.5 | 222.1 | 296.3 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 603 | 265.3 | 82.5 | 237.5 | 96.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 620 | 212.5 | 84.1 | --- | --- | --- | --- | C3'endo | 0.014 |
| 1 | DA | A | 637 | 277.6 | 89.2 | 244.3 | 102.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 646 | 220.2 | 288.2 | 237.5 | 273.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 781 | 354.0 | 99.6 | 0.0 | 68.1 | 357.2 | 18.5 | C3'endo | 0.018 |
| 1 | DA | G | 784 | 294.7 | 108.2 | 299.1 | 101.9 | 289.8 | 97.5 | C3'endo | 0.0 |
| 1 | DA | U | 846 | 278.1 | 109.9 | 282.6 | 91.4 | 288.0 | 64.3 | C3'endo | 0.0 |
| 1 | DA | A | 973 | 88.0 | 275.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | C | 995 | 349.1 | 140.9 | 6.5 | 119.0 | 1.0 | 61.1 | C3'endo | 0.128 |
| 1 | DA | C | 1045 | 206.6 | 69.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1046 | 334.8 | 40.0 | 341.3 | 16.8 | 133.7 | 8.2 | C3'endo | 0.0 |
| 1 | DA | A | 1088 | 302.4 | 52.5 | 303.7 | 55.7 | 293.5 | 53.1 | C3'endo | 0.0 |
| 1 | DA | U | 1141 | 237.9 | 93.6 | 239.0 | 89.0 | --- | --- | C3'endo | 0.198 |
| 1 | DA | A | 1156 | 47.9 | 298.7 | 68.3 | 285.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1175 | 254.0 | 353.3 | 279.4 | 344.1 | --- | --- | C3'endo | 0.049 |
| 1 | DA | U | 1312 | 222.8 | 113.0 | --- | --- | --- | --- | C3'endo | 0.208 |
| 1 | DA | U | 1340 | 205.3 | 295.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1396 | 353.9 | 313.8 | 7.1 | 296.5 | --- | --- | C3'endo | 0.256 |
| 1 | DA | U | 1523 | 34.6 | 313.6 | 40.1 | 309.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1535 | 89.2 | 289.1 | 80.4 | 305.9 | 88.7 | 351.1 | C3'endo | 0.0 |
| 1 | DA | C | 1536 | 217.6 | 100.3 | 251.9 | 86.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1554 | 97.7 | 281.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1583 | 205.6 | 60.8 | 245.6 | 9.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1584 | 48.8 | 281.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1693 | 87.0 | 320.8 | --- | --- | --- | --- | C3'endo | 0.065 |
| 1 | DA | A | 1713 | 54.8 | 263.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1729 | 111.6 | 338.3 | 100.7 | 323.0 | 80.6 | 341.7 | C3'endo | 0.0 |
| 1 | DA | A | 1757 | 348.4 | 333.5 | 348.7 | 313.6 | --- | --- | C3'endo | 0.482 |
| 1 | DA | A | 1913 | 124.1 | 139.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 1969 | 215.1 | 83.6 | --- | --- | --- | --- | C3'endo | 0.77 |
| 1 | DA | G | 1992 | 312.4 | 144.8 | 317.4 | 112.8 | --- | --- | C3'endo | 0.093 |
| 1 | DA | C | 2055 | 228.1 | 53.7 | 244.8 | 66.9 | 293.9 | 116.9 | C3'endo | 0.0 |
| 1 | DA | G | 2067 | 203.0 | 293.7 | --- | --- | --- | --- | C3'endo | 0.1 |
| 1 | DA | U | 2092 | 71.3 | 115.2 | 102.1 | 120.0 | 46.3 | 112.0 | C3'endo | 0.0 |
| 1 | DA | U | 2203 | 47.6 | 102.0 | 50.8 | 69.2 | 88.8 | 343.2 | C3'endo | 0.01 |
| 1 | DA | A | 2266 | 59.0 | 73.7 | 112.8 | 67.1 | 138.6 | 63.6 | C3'endo | 0.0 |
| 1 | DA | G | 2282 | 210.4 | 30.1 | 219.6 | 13.5 | 203.2 | 34.0 | C3'endo | 0.837 |
| 1 | DA | U | 2305 | 134.8 | 128.2 | 126.3 | 137.3 | 93.6 | 95.4 | C3'endo | 0.0 |
| 1 | DA | C | 2306 | 129.2 | 335.6 | 123.4 | 296.0 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 2307 | 60.7 | 88.9 | 93.3 | 78.6 | 116.9 | 53.1 | C3'endo | 0.025 |
| 1 | DA | A | 2311 | 236.3 | 286.2 | 234.7 | 283.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2320 | 277.1 | 71.6 | 265.1 | 48.8 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2321 | 106.3 | 278.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2324 | 202.2 | 359.2 | 211.2 | 324.2 | --- | --- | C3'endo | 0.033 |
| 1 | DA | G | 2382 | 236.1 | 65.7 | 226.1 | 69.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2401 | 201.2 | 291.9 | --- | --- | --- | --- | C3'endo | 0.014 |
| 1 | DA | U | 2402 | 232.4 | 81.8 | 267.2 | 96.3 | 298.6 | 91.0 | C3'endo | 0.0 |
| 1 | DA | U | 2423 | 10.2 | 109.3 | 9.7 | 81.2 | 343.1 | 32.0 | C3'endo | 0.0 |
| 1 | DA | C | 2424 | 42.5 | 16.4 | 43.2 | 340.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 2425 | 106.1 | 45.4 | 118.6 | 29.8 | --- | --- | C3'endo | 0.017 |
| 1 | DA | A | 2439 | 10.1 | 137.7 | 3.2 | 97.8 | 100.6 | 31.1 | C3'endo | 0.0 |
| 1 | DA | G | 2502 | 334.9 | 45.1 | 355.6 | 36.8 | 131.7 | 68.8 | C3'endo | 0.0 |
| 1 | DA | G | 2578 | 61.5 | 128.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2613 | 103.6 | 288.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 2797 | 48.9 | 76.8 | 68.2 | 21.8 | --- | --- | C3'endo | 0.473 |
| 1 | DA | U | 2798 | 75.9 | 113.8 | 111.8 | 123.5 | --- | --- | C3'endo | 0.0 |
| 1 | DB | C | 35 | 98.1 | 274.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | DB | G | 56 | 212.3 | 106.8 | --- | --- | --- | --- | C3'endo | 0.802 |
| 1 | DB | U | 87 | 99.0 | 298.9 | 88.5 | 305.8 | --- | --- | C3'endo | 0.0 |
| 1 | DB | A | 108 | 217.3 | 71.4 | --- | --- | --- | --- | C3'endo | 0.416 |
| 1 | AA | C | 83 | --- | --- | 240.3 | 133.7 | --- | --- | C3'endo | 0.0 |
| 1 | AA | A | 397 | --- | --- | 308.6 | 135.2 | --- | --- | C3'endo | 0.029 |
| 1 | AA | G | 484 | --- | --- | 119.5 | 98.1 | 129.5 | 86.2 | C3'endo | 0.0 |
| 1 | AA | C | 1031 | --- | --- | 150.9 | 74.0 | 165.8 | 83.5 | C3'endo | 0.0 |
| 1 | AA | A | 1319 | --- | --- | 240.4 | 135.8 | --- | --- | C3'endo | 0.049 |
| 1 | BA | A | 412 | --- | --- | 280.0 | 262.4 | --- | --- | C3'endo | 0.0 |
| 1 | BA | A | 547 | --- | --- | 240.8 | 269.8 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 562 | --- | --- | 295.8 | 157.3 | --- | --- | C3'endo | 0.439 |
| 1 | BA | A | 781 | --- | --- | 347.3 | 86.4 | 346.7 | 23.1 | C3'endo | 0.04 |
| 1 | BA | U | 1060 | --- | --- | 98.2 | 106.2 | 96.4 | 63.9 | C3'endo | 0.0 |
| 1 | BA | A | 1175 | --- | --- | 293.3 | 353.9 | 255.5 | 348.7 | C3'endo | 0.0 |
| 1 | BA | G | 1179 | --- | --- | 145.7 | 290.2 | --- | --- | C3'endo | 0.03 |
| 1 | BA | G | 1271 | --- | --- | 150.8 | 123.1 | --- | --- | C3'endo | 0.0 |
| 1 | BA | U | 1779 | --- | --- | 155.2 | 24.6 | 133.6 | 36.6 | C3'endo | 0.363 |
| 1 | BA | A | 1785 | --- | --- | 109.4 | 146.5 | 121.9 | 102.8 | C3'endo | 0.0 |
| 1 | BA | A | 1936 | --- | --- | 235.1 | 48.2 | 203.4 | 50.7 | C3'endo | 0.301 |
| 1 | BA | A | 2577 | --- | --- | 282.7 | 356.9 | --- | --- | C3'endo | 0.455 |
| 1 | BA | C | 2755 | --- | --- | 354.2 | 150.7 | 349.5 | 99.6 | C3'endo | 0.036 |
| 1 | CA | A | 109 | --- | --- | 128.0 | 287.2 | --- | --- | C3'endo | 0.251 |
| 1 | CA | A | 397 | --- | --- | 307.2 | 138.2 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 595 | --- | --- | 224.9 | 130.9 | --- | --- | C3'endo | 0.545 |
| 1 | CA | U | 632 | --- | --- | 217.3 | 346.8 | --- | --- | C3'endo | 0.066 |
| 1 | CA | C | 1137 | --- | --- | 220.9 | 78.1 | --- | --- | C3'endo | 0.0 |
| 1 | CA | A | 1285 | --- | --- | 113.4 | 129.3 | 136.7 | 76.0 | C3'endo | 0.0 |
| 1 | CA | A | 1398 | --- | --- | 151.4 | 84.1 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 141 | --- | --- | 149.2 | 300.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 321 | --- | --- | 15.9 | 273.0 | 355.9 | 305.4 | C3'endo | 0.047 |
| 1 | DA | G | 386 | --- | --- | 144.0 | 316.9 | 147.3 | 344.9 | C3'endo | 0.0 |
| 1 | DA | A | 454 | --- | --- | 299.9 | 307.9 | --- | --- | C3'endo | 0.349 |
| 1 | DA | U | 562 | --- | --- | 284.3 | 151.6 | --- | --- | C3'endo | 0.0 |
| 1 | DA | A | 613 | --- | --- | 85.6 | 286.1 | 67.2 | 0.6 | C3'endo | 0.0 |
| 1 | DA | U | 653 | --- | --- | 159.4 | 7.4 | 153.2 | 332.6 | C3'endo | 0.01 |
| 1 | DA | U | 762 | --- | --- | 251.3 | 103.3 | 195.3 | 51.4 | C3'endo | 0.433 |
| 1 | DA | U | 1033 | --- | --- | 19.5 | 167.7 | 352.3 | 122.2 | C3'endo | 0.0 |
| 1 | DA | U | 1060 | --- | --- | 108.1 | 76.3 | 42.6 | 23.0 | C3'endo | 0.0 |
| 1 | DA | A | 1265 | --- | --- | 122.9 | 138.9 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 1271 | --- | --- | 146.6 | 113.5 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1460 | --- | --- | 228.5 | 344.7 | --- | --- | C3'endo | 0.0 |
| 1 | DA | G | 1475 | --- | --- | 225.7 | 130.2 | --- | --- | C3'endo | 0.39 |
| 1 | DA | G | 1756 | --- | --- | 243.1 | 150.4 | --- | --- | C3'endo | 0.0 |
| 1 | DA | U | 1779 | --- | --- | 150.1 | 23.9 | 127.8 | 38.6 | C3'endo | 0.127 |
| 1 | DA | A | 1936 | --- | --- | 229.9 | 46.6 | 201.3 | 49.6 | C3'endo | 0.138 |
| 1 | DA | U | 2210 | --- | --- | 111.7 | 130.5 | 119.7 | 122.3 | C3'endo | 0.0 |
| 1 | DA | U | 2344 | --- | --- | 229.4 | 139.7 | --- | --- | C3'endo | 0.116 |
| 1 | DA | A | 2497 | --- | --- | 229.1 | 128.4 | 296.8 | 134.3 | C3'endo | 0.483 |
| 1 | DA | G | 2645 | --- | --- | 219.5 | 331.2 | 287.9 | 349.1 | C3'endo | 0.018 |
| 1 | DA | C | 2755 | --- | --- | 358.9 | 140.6 | 358.5 | 86.7 | C3'endo | 0.334 |
| 1 | DA | A | 2776 | --- | --- | 227.2 | 116.5 | --- | --- | C3'endo | 0.255 |
| 1 | DA | U | 2866 | --- | --- | 113.1 | 133.0 | 129.8 | 120.3 | C3'endo | 0.0 |
| 1 | DB | A | 66 | --- | --- | 230.1 | 125.5 | --- | --- | C3'endo | 0.0 |
| 1 | AA | U | 208 | --- | --- | --- | --- | 118.3 | 113.2 | C3'endo | 0.01 |
| 1 | AA | A | 665 | --- | --- | --- | --- | 16.9 | 155.2 | C3'endo | 0.0 |
| 1 | AA | A | 1167 | 47.9 | 286.1 | --- | --- | 41.8 | 149.5 | C3'endo | 0.0 |
| 1 | AA | C | 1336 | --- | --- | --- | --- | 185.7 | 77.3 | C3'endo | 0.241 |
| 1 | AA | A | 1492 | --- | --- | --- | --- | 108.0 | 135.7 | C3'endo | 0.0 |
| 1 | BA | A | 221 | 215.4 | 44.9 | --- | --- | 160.9 | 88.4 | C3'endo | 0.0 |
| 1 | BA | G | 549 | --- | --- | --- | --- | 167.2 | 38.0 | C3'endo | 0.0 |
| 1 | BA | A | 751 | 299.3 | 114.9 | --- | --- | 313.9 | 124.0 | C3'endo | 0.143 |
| 1 | BA | U | 827 | 4.5 | 46.5 | --- | --- | 323.4 | 27.2 | C3'endo | 0.0 |
| 1 | BA | U | 1033 | --- | --- | --- | --- | 354.2 | 144.4 | C3'endo | 0.0 |
| 1 | BA | A | 1086 | --- | --- | --- | --- | 283.7 | 86.4 | C3'endo | 0.577 |
| 1 | BA | A | 1274 | --- | --- | --- | --- | 19.1 | 136.8 | C3'endo | 0.01 |
| 1 | BA | A | 1583 | --- | --- | --- | --- | 292.0 | 353.7 | C3'endo | 0.0 |
| 1 | BA | C | 1646 | --- | --- | --- | --- | 194.7 | 37.4 | C3'endo | 0.082 |
| 1 | BA | C | 1870 | --- | --- | --- | --- | 348.1 | 309.2 | C3'endo | 0.448 |
| 1 | BA | A | 2333 | 209.4 | 111.9 | --- | --- | 186.0 | 31.9 | C3'endo | 0.0 |
| 1 | BA | G | 2529 | --- | --- | --- | --- | 44.9 | 340.0 | C3'endo | 0.0 |
| 1 | BA | G | 2688 | --- | --- | --- | --- | 262.6 | 356.9 | C3'endo | 0.194 |
| 1 | BA | A | 2872 | --- | --- | --- | --- | 117.7 | 140.6 | C3'endo | 0.218 |
| 1 | BA | A | 2883 | --- | --- | --- | --- | 181.7 | 14.5 | C3'endo | 0.0 |
| 1 | CA | U | 209 | 73.5 | 329.4 | --- | --- | 57.7 | 26.7 | C3'endo | 0.0 |
| 1 | CA | A | 279 | --- | --- | --- | --- | 138.3 | 331.9 | C3'endo | 0.46 |
| 1 | CA | A | 465 | --- | --- | --- | --- | 10.6 | 164.6 | C3'endo | 0.0 |
| 1 | CA | A | 665 | --- | --- | --- | --- | 9.3 | 151.0 | C3'endo | 0.0 |
| 1 | CA | G | 971 | 242.4 | 75.0 | --- | --- | 185.3 | 52.4 | C3'endo | 0.019 |
| 1 | CA | U | 1029 | 131.3 | 81.4 | --- | --- | 270.9 | 356.6 | C3'endo | 0.0 |
| 1 | CA | C | 1031 | --- | --- | --- | --- | 198.1 | 35.0 | C3'endo | 0.0 |
| 1 | CA | U | 1135 | --- | --- | --- | --- | 288.5 | 121.0 | C3'endo | 0.485 |
| 1 | CA | U | 1212 | 312.9 | 72.2 | --- | --- | 177.0 | 32.2 | C3'endo | 0.0 |
| 1 | CA | C | 1303 | --- | --- | --- | --- | 287.7 | 327.8 | C3'endo | 0.0 |
| 1 | CA | C | 1322 | --- | --- | --- | --- | 44.5 | 195.5 | C3'endo | 0.0 |
| 1 | CA | A | 1377 | --- | --- | --- | --- | 187.0 | 77.1 | C3'endo | 0.889 |
| 1 | CA | C | 1533 | --- | --- | --- | --- | 27.7 | 196.2 | C3'endo | 0.469 |
| 1 | DA | A | 49 | --- | --- | --- | --- | 129.5 | 329.7 | C3'endo | 0.0 |
| 1 | DA | U | 100 | --- | --- | --- | --- | 111.4 | 61.2 | C3'endo | 0.0 |
| 1 | DA | U | 139 | 45.5 | 1.6 | --- | --- | 70.7 | 357.1 | C3'endo | 0.0 |
| 1 | DA | A | 221 | --- | --- | --- | --- | 162.1 | 90.9 | C3'endo | 0.01 |
| 1 | DA | G | 370 | 219.4 | 336.2 | --- | --- | 186.6 | 341.0 | C3'endo | 0.023 |
| 1 | DA | C | 385 | --- | --- | --- | --- | 266.8 | 56.6 | C3'endo | 0.061 |
| 1 | DA | A | 404 | 225.3 | 112.8 | --- | --- | 188.4 | 58.5 | C3'endo | 0.0 |
| 1 | DA | U | 451 | --- | --- | --- | --- | 80.8 | 164.5 | C3'endo | 0.0 |
| 1 | DA | G | 489 | 61.8 | 263.1 | --- | --- | 60.3 | 184.9 | C3'endo | 0.109 |
| 1 | DA | G | 549 | --- | --- | --- | --- | 176.6 | 59.7 | C3'endo | 0.0 |
| 1 | DA | A | 644 | --- | --- | --- | --- | 162.4 | 80.1 | C3'endo | 0.33 |
| 1 | DA | A | 685 | 208.6 | 77.0 | --- | --- | 186.5 | 43.1 | C3'endo | 0.01 |
| 1 | DA | A | 751 | 294.2 | 121.7 | --- | --- | 316.4 | 130.7 | C3'endo | 0.0 |
| 1 | DA | U | 827 | 7.2 | 52.6 | --- | --- | 329.7 | 45.9 | C3'endo | 0.0 |
| 1 | DA | U | 931 | 330.9 | 274.4 | --- | --- | 34.8 | 195.7 | C3'endo | 0.351 |
| 1 | DA | A | 1086 | --- | --- | --- | --- | 285.8 | 92.9 | C3'endo | 0.334 |
| 1 | DA | C | 1646 | --- | --- | --- | --- | 187.8 | 42.3 | C3'endo | 0.0 |
| 1 | DA | A | 1808 | --- | --- | --- | --- | 344.3 | 303.7 | C3'endo | 0.0 |
| 1 | DA | C | 1870 | --- | --- | --- | --- | 6.6 | 315.4 | C3'endo | 0.0 |
| 1 | DA | C | 2104 | --- | --- | --- | --- | 286.5 | 97.5 | C3'endo | 0.0 |
| 1 | DA | A | 2309 | --- | --- | --- | --- | 127.1 | 331.9 | C3'endo | 0.0 |
| 1 | DA | G | 2458 | 209.1 | 126.7 | --- | --- | 290.8 | 125.8 | C3'endo | 0.085 |
| 1 | DA | U | 2477 | --- | --- | --- | --- | 258.1 | 35.7 | C3'endo | 0.461 |
| 1 | DA | G | 2529 | --- | --- | --- | --- | 36.1 | 333.0 | C3'endo | 0.0 |
| 1 | DA | G | 2688 | --- | --- | --- | --- | 266.7 | 4.9 | C3'endo | 0.142 |
| 1 | DA | A | 2750 | 55.7 | 322.6 | --- | --- | 102.8 | 120.5 | C3'endo | 0.0 |
| 1 | DA | U | 2796 | --- | --- | --- | --- | 147.6 | 104.9 | C3'endo | 0.033 |
| 1 | DA | A | 2820 | --- | --- | --- | --- | 43.2 | 350.0 | C3'endo | 0.0 |
| 1 | DA | A | 2872 | --- | --- | --- | --- | 121.9 | 141.5 | C3'endo | 0.0 |
| 1 | DA | A | 2883 | --- | --- | --- | --- | 175.0 | 348.6 | C3'endo | 0.0 |
| 1 | AA | A | 51 | 9.3 | 63.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | C | 90 | 129.0 | 158.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 121 | 48.9 | 249.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 413 | 148.3 | 57.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 532 | 353.1 | 233.2 | 311.5 | 219.2 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 723 | 357.4 | 67.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 975 | 35.9 | 57.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 983 | 142.9 | 273.6 | 144.6 | 265.1 | 149.8 | 289.2 | C2'endo | 0.0 |
| 1 | AA | G | 1138 | 122.8 | 193.8 | 96.8 | 202.6 | --- | --- | C2'endo | 0.0 |
| 1 | AA | C | 1140 | 109.4 | 218.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | G | 1160 | 106.8 | 227.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 102 | 338.6 | 216.4 | 348.6 | 197.5 | 343.1 | 145.2 | C2'endo | 0.01 |
| 1 | BA | U | 138 | 204.4 | 10.9 | 193.6 | 348.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 163 | 68.0 | 258.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 504 | 17.2 | 48.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 532 | 142.5 | 34.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 574 | 19.2 | 86.6 | 71.4 | 45.2 | --- | --- | C2'endo | 0.064 |
| 1 | BA | A | 782 | 97.2 | 96.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 859 | 111.1 | 183.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 974 | 81.9 | 77.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1133 | 137.8 | 78.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1134 | 327.7 | 138.2 | --- | --- | --- | --- | C2'endo | 0.067 |
| 1 | BA | G | 1252 | 340.4 | 247.6 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | BA | G | 1452 | 144.1 | 77.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1453 | 246.2 | 346.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 1609 | 338.3 | 238.0 | --- | --- | --- | --- | C2'endo | 0.027 |
| 1 | BA | A | 1938 | 6.8 | 253.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2030 | 43.4 | 55.8 | 38.3 | 63.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2031 | 119.7 | 91.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 2032 | 301.0 | 215.9 | 341.6 | 195.1 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2198 | 107.1 | 207.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 2491 | 109.9 | 184.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 2751 | 292.2 | 295.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 67 | 136.3 | 188.6 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | CA | U | 244 | 28.4 | 55.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 532 | 322.4 | 244.2 | 303.3 | 205.3 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 793 | 139.8 | 330.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 820 | 169.6 | 5.4 | --- | --- | --- | --- | C2'endo | 0.088 |
| 1 | CA | A | 935 | 59.7 | 232.7 | 68.6 | 218.3 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 983 | 152.4 | 278.4 | 157.4 | 272.7 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 994 | 64.7 | 238.8 | --- | --- | --- | --- | C2'endo | 0.213 |
| 1 | CA | U | 1168 | 246.9 | 348.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1286 | 59.2 | 254.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 85 | 245.7 | 184.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 101 | 116.3 | 50.6 | 139.6 | 328.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 102 | 324.0 | 226.0 | 24.7 | 199.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 126 | 310.6 | 189.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 127 | 159.2 | 36.3 | 196.5 | 11.7 | --- | --- | C2'endo | 0.054 |
| 1 | DA | A | 233 | 261.1 | 260.7 | 284.1 | 237.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 323 | 95.6 | 58.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 334 | 148.1 | 63.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 335 | 30.8 | 219.0 | 88.8 | 208.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 372 | 275.9 | 47.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 444 | 89.6 | 145.3 | 82.4 | 162.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 455 | 154.2 | 265.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 481 | 147.5 | 47.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 504 | 5.6 | 49.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 574 | 28.2 | 84.8 | 73.7 | 47.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 621 | 145.6 | 261.3 | 140.3 | 260.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 671 | 357.9 | 204.2 | 351.5 | 189.7 | 352.6 | 222.7 | C2'endo | 0.0 |
| 1 | DA | A | 866 | 109.9 | 230.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1062 | 277.5 | 216.7 | 332.4 | 198.8 | 324.9 | 244.9 | C2'endo | 0.04 |
| 1 | DA | A | 1070 | 133.0 | 334.3 | 95.5 | 324.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1072 | 121.6 | 39.9 | 185.9 | 347.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1112 | 271.5 | 163.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1127 | 130.3 | 164.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1133 | 129.0 | 93.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1252 | 359.6 | 236.4 | 38.2 | 205.5 | --- | --- | C2'endo | 0.195 |
| 1 | DA | A | 1254 | 170.2 | 23.6 | 222.0 | 340.1 | --- | --- | C2'endo | 0.049 |
| 1 | DA | A | 1275 | 109.3 | 177.4 | 91.5 | 200.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1287 | 41.6 | 233.0 | 50.1 | 235.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1344 | 153.5 | 7.8 | 192.9 | 332.4 | --- | --- | C2'endo | 0.016 |
| 1 | DA | G | 1452 | 143.5 | 93.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1453 | 267.0 | 290.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1454 | 110.0 | 212.1 | 165.2 | 211.8 | --- | --- | C2'endo | 0.055 |
| 1 | DA | G | 1492 | 148.6 | 350.1 | 177.8 | 335.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1609 | 324.2 | 248.0 | --- | --- | --- | --- | C2'endo | 0.016 |
| 1 | DA | U | 1714 | 297.1 | 3.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1930 | 153.5 | 59.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1963 | 64.7 | 243.3 | 76.9 | 233.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1964 | 285.7 | 349.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2031 | 133.0 | 67.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2033 | 255.9 | 259.4 | 309.5 | 189.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2034 | 0.7 | 236.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 2146 | 23.9 | 193.5 | 60.3 | 184.0 | --- | --- | C2'endo | 0.033 |
| 1 | DA | A | 2147 | 207.3 | 5.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 2338 | 127.2 | 192.6 | 174.3 | 192.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 2385 | 323.8 | 198.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2491 | 125.5 | 173.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 2682 | 118.5 | 210.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 2751 | 278.8 | 283.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | DB | C | 42 | 112.2 | 206.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | AA | A | 8 | --- | --- | 275.8 | 238.0 | 265.0 | 261.6 | C2'endo | 0.0 |
| 1 | AA | A | 50 | --- | --- | 81.0 | 96.3 | 90.2 | 116.4 | C2'endo | 0.0 |
| 1 | AA | A | 702 | --- | --- | 19.0 | 354.8 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 139 | --- | --- | 68.1 | 224.1 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 140 | --- | --- | 278.1 | 14.0 | --- | --- | C2'endo | 0.0 |
| 1 | BA | G | 141 | --- | --- | 175.8 | 281.9 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 272 | --- | --- | 164.4 | 187.6 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 457 | --- | --- | 16.6 | 140.3 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 615 | --- | --- | 298.9 | 319.1 | 270.8 | 359.2 | C2'endo | 0.0 |
| 1 | BA | A | 627 | --- | --- | 68.5 | 141.4 | --- | --- | C2'endo | 0.0 |
| 1 | BA | U | 1132 | --- | --- | 166.6 | 298.5 | --- | --- | C2'endo | 0.0 |
| 1 | BA | C | 1454 | --- | --- | 147.6 | 195.7 | --- | --- | C2'endo | 0.179 |
| 1 | BA | A | 2134 | --- | --- | 63.8 | 198.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2135 | --- | --- | 169.3 | 206.2 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2147 | --- | --- | 230.1 | 342.2 | 265.0 | 26.5 | C2'endo | 0.0 |
| 1 | BA | U | 2690 | --- | --- | 150.1 | 257.6 | --- | --- | C2'endo | 0.0 |
| 1 | BA | A | 2799 | --- | --- | 164.5 | 195.6 | --- | --- | C2'endo | 0.0 |
| 1 | BB | G | 41 | --- | --- | 339.7 | 314.7 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 8 | --- | --- | 277.2 | 237.4 | 295.7 | 264.4 | C2'endo | 0.0 |
| 1 | CA | A | 50 | --- | --- | 79.3 | 107.3 | 89.3 | 122.7 | C2'endo | 0.048 |
| 1 | CA | C | 73 | --- | --- | 178.0 | 209.9 | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 330 | --- | --- | 20.3 | 198.4 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 368 | --- | --- | 311.9 | 356.3 | 327.4 | 76.9 | C2'endo | 0.06 |
| 1 | CA | G | 413 | --- | --- | 166.5 | 74.3 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 533 | --- | --- | 38.2 | 222.0 | --- | --- | C2'endo | 0.0 |
| 1 | CA | G | 1050 | --- | --- | 77.7 | 190.2 | --- | --- | C2'endo | 0.0 |
| 1 | CA | U | 1125 | --- | --- | 159.7 | 197.6 | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 1141 | --- | --- | 170.1 | 207.0 | --- | --- | C2'endo | 0.0 |
| 1 | CA | C | 1147 | --- | --- | 175.4 | 204.2 | --- | --- | C2'endo | 0.0 |
| 1 | CA | A | 1201 | --- | --- | 30.0 | 100.2 | 64.9 | 124.0 | C2'endo | 0.0 |
| 1 | CA | A | 1216 | --- | --- | 178.5 | 197.6 | --- | --- | C2'endo | 0.01 |
| 1 | CA | A | 1287 | --- | --- | 332.6 | 188.5 | 330.8 | 245.3 | C2'endo | 0.0 |
| 1 | DA | A | 223 | --- | --- | 327.3 | 3.8 | 341.0 | 79.6 | C2'endo | 0.0 |
| 1 | DA | C | 302 | --- | --- | 173.0 | 196.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 330 | --- | --- | 152.2 | 209.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 388 | --- | --- | 143.6 | 199.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 457 | --- | --- | 25.5 | 134.4 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 475 | --- | --- | 335.6 | 247.3 | 333.8 | 274.6 | C2'endo | 0.0 |
| 1 | DA | G | 729 | --- | --- | 321.3 | 0.2 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 789 | --- | --- | 251.5 | 309.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 932 | --- | --- | 55.0 | 71.2 | 29.9 | 35.0 | C2'endo | 0.0 |
| 1 | DA | U | 1012 | --- | --- | 300.9 | 32.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1061 | --- | --- | 39.7 | 225.1 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1073 | --- | --- | 75.3 | 202.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1076 | --- | --- | 177.2 | 207.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1079 | --- | --- | 174.4 | 205.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1129 | --- | --- | 172.5 | 60.8 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1132 | --- | --- | 165.3 | 291.3 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1134 | --- | --- | 345.0 | 122.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | C | 1135 | --- | --- | 321.5 | 245.4 | 326.0 | 212.9 | C2'endo | 0.0 |
| 1 | DA | A | 1205 | --- | --- | 346.8 | 339.9 | 286.4 | 29.3 | C2'endo | 0.0 |
| 1 | DA | U | 1255 | --- | --- | 334.5 | 343.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 1273 | --- | --- | 48.2 | 111.8 | 61.5 | 84.8 | C2'endo | 0.0 |
| 1 | DA | C | 1386 | --- | --- | 163.4 | 191.5 | --- | --- | C2'endo | 0.0 |
| 1 | DA | A | 1387 | --- | --- | 174.5 | 202.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1416 | --- | --- | 316.2 | 150.9 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1538 | --- | --- | 301.2 | 168.7 | --- | --- | C2'endo | 0.0 |
| 1 | DA | G | 1715 | --- | --- | 37.7 | 104.8 | 75.9 | 113.3 | C2'endo | 0.0 |
| 1 | DA | C | 1816 | --- | --- | 294.4 | 28.0 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2348 | --- | --- | 165.5 | 207.6 | --- | --- | C2'endo | 0.0 |
| 1 | DA | U | 2833 | --- | --- | 331.3 | 14.8 | --- | --- | C2'endo | 0.0 |
| 1 | AA | U | 88 | --- | --- | --- | --- | 305.3 | 229.2 | C2'endo | 0.0 |
| 1 | AA | U | 485 | --- | --- | --- | --- | 4.3 | 157.6 | C2'endo | 0.0 |
| 1 | AA | U | 561 | --- | --- | --- | --- | 62.7 | 117.7 | C2'endo | 0.034 |
| 1 | AA | C | 1054 | --- | --- | --- | --- | 342.5 | 80.2 | C2'endo | 0.0 |
| 1 | AA | U | 1183 | --- | --- | --- | --- | 0.5 | 205.9 | C2'endo | 0.0 |
| 1 | AA | A | 1201 | --- | --- | --- | --- | 89.5 | 106.5 | C2'endo | 0.0 |
| 1 | AA | A | 1227 | 74.3 | 231.7 | --- | --- | 110.3 | 264.0 | C2'endo | 0.0 |
| 1 | AA | U | 1240 | --- | --- | --- | --- | 19.3 | 11.0 | C2'endo | 0.0 |
| 1 | BA | C | 323 | 100.5 | 40.2 | --- | --- | 164.0 | 28.5 | C2'endo | 0.408 |
| 1 | BA | U | 1061 | --- | --- | --- | --- | 32.9 | 224.1 | C2'endo | 0.0 |
| 1 | BA | A | 1205 | --- | --- | --- | --- | 311.0 | 15.6 | C2'endo | 0.0 |
| 1 | BA | G | 1715 | --- | --- | --- | --- | 84.1 | 120.4 | C2'endo | 0.0 |
| 1 | BA | G | 2345 | --- | --- | --- | --- | 19.9 | 83.6 | C2'endo | 0.0 |
| 1 | BA | A | 2406 | --- | --- | --- | --- | 160.6 | 290.8 | C2'endo | 0.0 |
| 1 | CA | A | 65 | --- | --- | --- | --- | 356.6 | 9.6 | C2'endo | 0.0 |
| 1 | CA | U | 561 | --- | --- | --- | --- | 57.0 | 114.4 | C2'endo | 0.325 |
| 1 | CA | A | 563 | --- | --- | --- | --- | 102.1 | 27.1 | C2'endo | 0.0 |
| 1 | CA | A | 975 | 32.6 | 74.2 | --- | --- | 89.7 | 92.9 | C2'endo | 0.0 |
| 1 | CA | U | 1183 | --- | --- | --- | --- | 355.8 | 208.9 | C2'endo | 0.0 |
| 1 | DA | A | 216 | --- | --- | --- | --- | 265.5 | 237.5 | C2'endo | 0.0 |
| 1 | DA | C | 484 | --- | --- | --- | --- | 265.7 | 241.2 | C2'endo | 0.01 |
| 1 | DA | C | 2023 | 333.5 | 199.1 | --- | --- | 33.3 | 207.5 | C2'endo | 0.0 |
| 1 | DA | C | 2215 | --- | --- | --- | --- | 257.5 | 240.7 | C2'endo | 0.0 |
| 1 | DA | G | 2250 | --- | --- | --- | --- | 342.2 | 250.6 | C2'endo | 0.0 |
| 1 | DA | G | 2345 | --- | --- | --- | --- | 18.2 | 91.7 | C2'endo | 0.0 |
| 1 | DA | A | 2602 | --- | --- | --- | --- | 12.3 | 16.6 | C2'endo | 0.0 |