EMDataResource Pseudotorsion Plot Beta Server
RNA adopts complex three-dimensional folding patterns and has key roles in many cellular functions. Many cryoEM-derived structures contain RNA, including ribosomal particles, spliceosomes, RNA viruses, and polymerase complexes, yet procedures for validation of RNA structures are not as well developed as those for proteins.
This prototype web-service for virtual torsion angle validation of RNA structures can be applied to structures determined using cryo-EM as well as other structural methods. Virtual torsion angle plots for nucleic acids are analogous to Ramachandran plots for proteins. The tool evaluates single structures, either by file upload (mmCIF or PDB format) or by entering a PDB id.
The research community has developed simplified ways to represent nucleic acid backbone conformation through use of virtual torsion angles1-3. A common scheme is to define two virtual torsion angles (pseudotorsions), eta (η) and theta (θ) for a nucleotide triplet. The measured (η,θ) pair defines the backbone conformation relative to central residue (i).
The server calculates three varieties of pseudotorsion angles, as shown in the image below. In all definitions, phosphate atom positions are used, but the alternate atom differs: it is either the C4' atom (η,θ), C1' atom (η',θ'), or base origin4,5 position (η",θ").
Virtual torsion angles of the RNA backbone (calculated using DSSR4) are compared against the statistical distribution of a benchmark set of high quality, non-redundant6 RNA structures determined by X-ray crystallography at ≤ 2.5 Å. Separate analyses are performed based on sugar-puckering type (of ~27,000 residues in the benchmark set, ~24,000 are C3'-endo-like, ~3,000 are C2'-endo-like). Output plots and and a downloadable (csv format) table identify probable conformational outliers for any given RNA-containing structure. For comparison, RNA Suiteness7,8 scores are also provided in the csv (for residue i, suiteness of the i-1, i dinucleotide is listed. Suiteness range is 0(poor)-1(excellent). Calculation performed using DSSR).
The 2D plots permit comparison of pseudotorsion pairs for the structure being evaluated (plotted points) against population statistics of the benchmark set (smoothed contours: bar at right indicates benchmark residue count range). Outliers are marked on the plots by red crosses with residue information available on mouse hover. Summary statistics are provided below each plot to indicate the number of residues evaluated and percent outliers. Note that pseudotorsion angles cannot be calculated for terminal residues or around breaks in the polymer chain, so these are excluded from evaluation.
This tool is designed to identify regions of unusual conformation in folded RNA. Outliers can be legitimate but less-common backbone conformations, or they may indicate modelling error.
It may take several minutes to complete calculations for large structures such as ribosomes.
Please direct any questions/suggestions to help@emdataresource.org
- Olson, W. K. Configurational statistics of polynucleotide chains. An updated virtual bond model to treat effects of base stacking. Macromolecules 13, 721-728 (1980).
- Wadley, L. M., Keating, K. S., Duarte, C. M. & Pyle, A. M. Evaluating and learning from RNA pseudotorsional space: quantitative validation of a reduced representation for RNA structure. J Mol Biol 372, 942-957, doi (2007).
- Keating, K. S., Humphris, E. L. & Pyle, A. M. A new way to see RNA. Q Rev Biophys 44, 433-466, doi (2011).
- Lu, X. J., Bussemaker, H. J. & Olson, W. K. DSSR: an integrated software tool for dissecting the spatial structure of RNA. Nucleic Acids Res 43, e142, doi (2015).
- Li, S., Olson, W. K., Lu, X. J. Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures. Nucleic Acids Research 47, W26-W34 (2019). doi
- Leontis, N. B., & Zirbel, C. L. Nonredundant 3D Structure Datasets for RNA Knowledge Extraction and Benchmarking. In RNA 3D Structure Analysis and Prediction, N. Leontis & E. Westhof (Eds.), (Vol. 27, pp. 281-298). Springer Berlin Heidelberg. doi (2012).
- Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R.M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., Berman, H. M. RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). RNA 14, 465-81, doi (2008).
- Chen, V. B., Arendall III, W. B., Headd, J. J., Keedy, D. A., Immormino, R. M., Kapral, G. J., Murray, L. W., Richardson, J. S., Richardson, D. C., MolProbity: all-atom structure validation for macromolecular crystallography, Acta Cryst D 66, 12-21, doi (2010)
RNA Pseudotorsion Plots for PDB entry 4v88
The structure of the eukaryotic ribosome at 3.0 A resolution. Deposited 2011-10-11 X-RAY DIFFRACTION resol 3 Å
8599 C3'-endo RNA residues with 182 outliers ( 2.12 % ) from Eta-Theta plot
1667 C2'-endo RNA residues with 209 outliers ( 12.54 % ) from Eta-Theta plot
8599 C3'-endo RNA residues with 156 outliers ( 1.81 % ) from Eta'-Theta' plot
1667 C2'-endo RNA residues with 173 outliers ( 10.38 % ) from Eta'-Theta' plot
8560 C3'-endo RNA residues with 149 outliers ( 1.74 % ) from Eta"-Theta" plot
1663 C2'-endo RNA residues with 143 outliers ( 8.6 % ) from Eta"-Theta" plot
List of Outliers
| Model Number | Chain | Residue Type | Residue Identifier | Eta | Theta | Eta' | Theta' | Eta'' | Theta'' | Sugar Pucker | Suiteness |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | A2 | U | 134 | 354.0 | 149.6 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | C | 160 | 232.6 | 260.7 | --- | --- | --- | --- | C3'endo | 0.01 |
| 1 | A2 | U | 192 | 232.2 | 93.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | G | 234 | 109.2 | 278.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 277 | 3.4 | 9.1 | 70.0 | 305.4 | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 280 | 235.6 | 62.1 | 275.0 | 86.2 | 299.9 | 121.2 | C3'endo | 0.0 |
| 1 | A2 | A | 316 | 259.6 | 135.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | C | 424 | 75.8 | 113.1 | 79.8 | 77.1 | 98.2 | 3.5 | C3'endo | 0.0 |
| 1 | A2 | A | 425 | 13.2 | 109.9 | 5.8 | 124.2 | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 507 | 255.7 | 313.7 | 275.0 | 262.4 | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 558 | 248.8 | 75.4 | 264.6 | 82.9 | 304.2 | 95.4 | C3'endo | 0.0 |
| 1 | A2 | G | 577 | 196.8 | 43.3 | --- | --- | --- | --- | C3'endo | 0.266 |
| 1 | A2 | A | 579 | 340.4 | 282.2 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 608 | 323.5 | 103.0 | 340.7 | 113.0 | 73.7 | 112.1 | C3'endo | 0.218 |
| 1 | A2 | U | 705 | 231.4 | 131.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 766 | 120.4 | 312.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | U | 781 | 358.5 | 114.2 | 10.0 | 114.5 | 94.4 | 88.3 | C3'endo | 0.0 |
| 1 | A2 | U | 864 | 298.6 | 93.2 | 343.7 | 63.5 | 43.4 | 349.8 | C3'endo | 0.0 |
| 1 | A2 | C | 934 | 277.7 | 82.4 | 302.4 | 76.2 | 312.7 | 55.7 | C3'endo | 0.391 |
| 1 | A2 | U | 965 | 124.7 | 309.6 | 117.2 | 312.0 | --- | --- | C3'endo | 0.051 |
| 1 | A2 | U | 1052 | 243.7 | 54.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A2 | G | 1150 | 50.7 | 104.0 | 55.9 | 53.9 | --- | --- | C3'endo | 0.01 |
| 1 | A2 | G | 1201 | 69.9 | 279.9 | 57.3 | 286.5 | 60.2 | 118.5 | C3'endo | 0.239 |
| 1 | A2 | G | 1218 | 87.7 | 18.7 | 129.7 | 54.8 | 136.7 | 100.0 | C3'endo | 0.0 |
| 1 | A2 | U | 1390 | 289.7 | 92.8 | 313.0 | 114.5 | 304.4 | 140.4 | C3'endo | 0.0 |
| 1 | A2 | G | 1458 | 203.4 | 295.9 | 244.2 | 286.3 | --- | --- | C3'endo | 0.017 |
| 1 | A2 | C | 1537 | 297.8 | 84.7 | 318.2 | 72.7 | 286.0 | 67.9 | C3'endo | 0.0 |
| 1 | A2 | A | 1559 | 210.7 | 312.8 | 219.4 | 301.0 | --- | --- | C3'endo | 0.0 |
| 1 | A2 | N | 1697 | 86.4 | 319.7 | 142.2 | 284.9 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 67 | 304.6 | 342.0 | 325.3 | 11.2 | 348.4 | 93.0 | C3'endo | 0.179 |
| 1 | A1 | G | 92 | 122.4 | 306.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 284 | 292.7 | 61.5 | 24.5 | 61.5 | 56.7 | 87.6 | C3'endo | 0.017 |
| 1 | A1 | U | 298 | 328.3 | 43.8 | 326.7 | 37.7 | 62.7 | 53.9 | C3'endo | 0.0 |
| 1 | A1 | A | 351 | 329.5 | 146.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 375 | 111.2 | 302.9 | --- | --- | --- | --- | C3'endo | 0.011 |
| 1 | A1 | G | 421 | 40.6 | 98.5 | 91.2 | 99.1 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 545 | 329.4 | 122.7 | 8.2 | 107.0 | 49.0 | 117.2 | C3'endo | 0.085 |
| 1 | A1 | G | 609 | 111.0 | 33.5 | 113.8 | 89.7 | 109.8 | 115.3 | C3'endo | 0.0 |
| 1 | A1 | G | 916 | 306.4 | 107.9 | 306.9 | 97.1 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 1001 | 34.5 | 8.1 | 53.7 | 332.0 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 1029 | 86.4 | 133.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 1159 | 230.9 | 135.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 1237 | 264.7 | 281.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | C | 1248 | 281.4 | 297.1 | 263.0 | 285.2 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 1309 | 27.5 | 318.6 | 62.7 | 284.5 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | C | 1316 | 322.2 | 26.8 | --- | --- | --- | --- | C3'endo | 0.18 |
| 1 | A1 | U | 1356 | 38.5 | 321.4 | 39.4 | 323.6 | 107.9 | 336.6 | C3'endo | 0.0 |
| 1 | A1 | A | 1399 | 46.6 | 69.6 | 14.7 | 65.4 | 328.3 | 25.0 | C3'endo | 0.0 |
| 1 | A1 | C | 1644 | 140.5 | 87.5 | --- | --- | --- | --- | C3'endo | 0.01 |
| 1 | A1 | U | 1687 | 291.3 | 50.0 | 313.5 | 46.6 | 303.0 | 71.1 | C3'endo | 0.15 |
| 1 | A1 | C | 1779 | 312.5 | 272.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 2115 | 339.2 | 333.1 | 341.4 | 316.9 | --- | --- | C3'endo | 0.592 |
| 1 | A1 | C | 2308 | 255.6 | 340.7 | 313.1 | 295.1 | --- | --- | C3'endo | 0.01 |
| 1 | A1 | A | 2312 | 211.7 | 70.3 | --- | --- | --- | --- | C3'endo | 0.942 |
| 1 | A1 | A | 2397 | 258.8 | 11.9 | 277.6 | 32.9 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 2410 | 249.3 | 70.0 | 279.7 | 75.4 | 306.7 | 91.1 | C3'endo | 0.139 |
| 1 | A1 | A | 2626 | 105.6 | 9.8 | 95.1 | 324.3 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 2690 | 125.4 | 338.2 | 123.1 | 307.9 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 2777 | 131.5 | 121.4 | 144.0 | 93.0 | 163.1 | 10.8 | C3'endo | 0.0 |
| 1 | A1 | A | 2799 | 302.1 | 100.4 | 291.8 | 95.7 | 181.2 | 85.1 | C3'endo | 0.0 |
| 1 | A1 | C | 2942 | 257.7 | 67.5 | 257.8 | 66.0 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 2946 | 284.1 | 41.5 | 271.6 | 17.4 | 192.1 | 337.4 | C3'endo | 0.167 |
| 1 | A1 | G | 2947 | 44.0 | 118.3 | 47.7 | 150.8 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 2971 | 68.7 | 55.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 3058 | 277.8 | 82.9 | 303.3 | 99.0 | 308.9 | 91.4 | C3'endo | 0.0 |
| 1 | A1 | A | 3142 | 284.4 | 304.9 | 306.1 | 289.0 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 3178 | 303.8 | 142.1 | 321.6 | 121.4 | --- | --- | C3'endo | 0.22 |
| 1 | A1 | A | 3245 | 239.7 | 304.1 | 272.4 | 303.7 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 3275 | 319.4 | 308.2 | 347.9 | 296.1 | --- | --- | C3'endo | 0.371 |
| 1 | A1 | U | 3319 | 10.9 | 325.5 | 5.7 | 305.7 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 3351 | 57.7 | 265.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 3354 | 213.3 | 68.0 | 246.9 | 62.6 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | G | 3369 | 330.1 | 80.4 | 304.2 | 74.4 | 305.9 | 72.9 | C3'endo | 0.0 |
| 1 | A1 | A | 3376 | 119.0 | 337.2 | 105.3 | 292.6 | --- | --- | C3'endo | 0.0 |
| 1 | A3 | A | 64 | 298.9 | 330.5 | 337.5 | 329.4 | --- | --- | C3'endo | 0.408 |
| 1 | A3 | C | 73 | 12.8 | 110.8 | 18.7 | 84.3 | 16.7 | 19.7 | C3'endo | 0.0 |
| 1 | A4 | A | 80 | 233.1 | 109.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A4 | U | 86 | 301.1 | 78.7 | 298.1 | 84.4 | 290.8 | 59.1 | C3'endo | 0.0 |
| 1 | A4 | U | 113 | 266.4 | 31.6 | 296.5 | 61.0 | 312.8 | 101.1 | C3'endo | 0.0 |
| 1 | A4 | U | 125 | 272.3 | 33.5 | 6.5 | 299.3 | --- | --- | C3'endo | 0.0 |
| 1 | A4 | C | 151 | 299.3 | 137.4 | 321.2 | 118.0 | 309.5 | 78.4 | C3'endo | 0.0 |
| 1 | A6 | U | 74 | 203.1 | 293.8 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A6 | C | 160 | 239.7 | 258.2 | --- | --- | --- | --- | C3'endo | 0.227 |
| 1 | A6 | U | 192 | 218.9 | 84.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A6 | U | 277 | 57.2 | 300.0 | 78.0 | 280.4 | --- | --- | C3'endo | 0.0 |
| 1 | A6 | C | 424 | 88.8 | 111.3 | 87.2 | 73.4 | 103.6 | 353.9 | C3'endo | 0.0 |
| 1 | A6 | A | 425 | 14.3 | 110.7 | 8.7 | 116.6 | --- | --- | C3'endo | 0.0 |
| 1 | A6 | C | 495 | 97.7 | 278.1 | 124.9 | 299.6 | --- | --- | C3'endo | 0.0 |
| 1 | A6 | A | 541 | 36.3 | 292.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A6 | U | 558 | 230.4 | 79.7 | 251.6 | 84.1 | 285.1 | 78.8 | C3'endo | 0.0 |
| 1 | A6 | A | 579 | 343.4 | 281.1 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A6 | U | 766 | 111.8 | 316.3 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A6 | U | 864 | 312.9 | 85.2 | 349.0 | 60.4 | 41.5 | 349.2 | C3'endo | 0.06 |
| 1 | A6 | C | 934 | 272.5 | 87.0 | 302.9 | 76.5 | 318.7 | 52.6 | C3'endo | 0.484 |
| 1 | A6 | U | 965 | 129.8 | 301.5 | 116.8 | 307.4 | --- | --- | C3'endo | 0.563 |
| 1 | A6 | A | 1027 | 71.8 | 25.4 | --- | --- | --- | --- | C3'endo | 0.176 |
| 1 | A6 | U | 1052 | 292.9 | 142.5 | 346.1 | 155.4 | 358.8 | 129.2 | C3'endo | 0.0 |
| 1 | A6 | G | 1150 | 56.5 | 78.9 | --- | --- | --- | --- | C3'endo | 0.019 |
| 1 | A6 | G | 1201 | 75.5 | 273.5 | 59.3 | 280.6 | 51.0 | 127.3 | C3'endo | 0.468 |
| 1 | A6 | G | 1458 | 207.7 | 296.7 | 235.9 | 286.2 | --- | --- | C3'endo | 0.0 |
| 1 | A6 | U | 1491 | 260.5 | 67.1 | 245.0 | 88.2 | 294.7 | 95.2 | C3'endo | 0.0 |
| 1 | A6 | A | 1559 | 212.1 | 314.5 | 228.4 | 282.8 | --- | --- | C3'endo | 0.0 |
| 1 | A6 | N | 1697 | 86.1 | 342.8 | 142.8 | 296.7 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 67 | 304.5 | 340.5 | 324.7 | 10.5 | 347.9 | 96.6 | C3'endo | 0.157 |
| 1 | A5 | G | 92 | 120.1 | 301.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 284 | 295.2 | 62.3 | 18.6 | 60.4 | 54.8 | 84.5 | C3'endo | 0.0 |
| 1 | A5 | U | 298 | 330.7 | 42.2 | 325.6 | 40.6 | 132.2 | 50.6 | C3'endo | 0.014 |
| 1 | A5 | A | 351 | 328.3 | 140.5 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 375 | 110.6 | 298.7 | --- | --- | --- | --- | C3'endo | 0.045 |
| 1 | A5 | G | 421 | 55.9 | 95.9 | 93.2 | 101.3 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 438 | 236.3 | 270.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | G | 609 | 115.3 | 33.9 | 112.8 | 88.4 | 108.1 | 113.6 | C3'endo | 0.0 |
| 1 | A5 | G | 860 | 270.8 | 22.8 | --- | --- | --- | --- | C3'endo | 0.428 |
| 1 | A5 | G | 916 | 310.5 | 106.0 | 308.7 | 95.5 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | G | 1001 | 44.9 | 355.0 | 59.2 | 330.4 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | G | 1024 | 76.8 | 266.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 1025 | 46.0 | 273.5 | 71.5 | 283.4 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 1028 | 266.3 | 109.4 | 303.2 | 85.1 | 30.9 | 23.9 | C3'endo | 0.0 |
| 1 | A5 | U | 1081 | 3.8 | 82.6 | 346.6 | 66.8 | 329.0 | 49.7 | C3'endo | 0.0 |
| 1 | A5 | A | 1103 | 115.6 | 325.7 | 115.3 | 317.6 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 1159 | 227.6 | 130.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 1309 | 23.4 | 319.8 | 61.9 | 281.2 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | C | 1316 | 319.8 | 26.8 | --- | --- | --- | --- | C3'endo | 0.271 |
| 1 | A5 | U | 1356 | 32.3 | 328.5 | 32.7 | 328.8 | 132.3 | 344.1 | C3'endo | 0.0 |
| 1 | A5 | A | 1399 | 58.1 | 63.9 | 20.2 | 60.5 | 323.7 | 24.6 | C3'endo | 0.0 |
| 1 | A5 | A | 1481 | 241.9 | 58.4 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 1568 | 249.4 | 87.1 | 246.2 | 94.6 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | C | 1581 | 13.9 | 34.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | C | 1644 | 138.5 | 90.0 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 1687 | 291.3 | 49.8 | 315.4 | 47.1 | 306.5 | 74.1 | C3'endo | 0.115 |
| 1 | A5 | U | 1717 | 272.1 | 143.9 | 307.4 | 160.7 | 342.3 | 174.0 | C3'endo | 0.0 |
| 1 | A5 | U | 1764 | 122.6 | 299.9 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | C | 1779 | 325.6 | 278.0 | --- | --- | --- | --- | C3'endo | 0.428 |
| 1 | A5 | G | 2115 | 339.1 | 331.6 | 341.5 | 315.0 | --- | --- | C3'endo | 0.657 |
| 1 | A5 | C | 2308 | 258.2 | 340.6 | 313.9 | 294.4 | --- | --- | C3'endo | 0.04 |
| 1 | A5 | A | 2312 | 216.1 | 68.6 | --- | --- | --- | --- | C3'endo | 0.945 |
| 1 | A5 | U | 2314 | 77.4 | 288.5 | 52.1 | 300.2 | --- | --- | C3'endo | 0.131 |
| 1 | A5 | U | 2410 | 251.2 | 67.8 | 281.2 | 76.0 | 306.1 | 93.2 | C3'endo | 0.041 |
| 1 | A5 | A | 2626 | 106.5 | 5.3 | 93.8 | 323.1 | --- | --- | C3'endo | 0.032 |
| 1 | A5 | G | 2690 | 125.3 | 340.0 | 126.3 | 308.0 | --- | --- | C3'endo | 0.011 |
| 1 | A5 | A | 2799 | 297.0 | 101.6 | 282.2 | 96.9 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | G | 2871 | 329.9 | 49.5 | 357.1 | 23.6 | 132.5 | 24.2 | C3'endo | 0.0 |
| 1 | A5 | C | 2942 | 260.3 | 66.6 | 261.3 | 66.8 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 2946 | 285.1 | 41.3 | 270.1 | 15.9 | 193.6 | 339.4 | C3'endo | 0.04 |
| 1 | A5 | G | 2947 | 42.5 | 116.7 | 47.9 | 149.2 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 2971 | 117.1 | 47.4 | 110.7 | 3.9 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 3058 | 276.7 | 86.9 | 301.8 | 98.8 | --- | --- | C3'endo | 0.316 |
| 1 | A5 | A | 3142 | 278.9 | 308.7 | 302.9 | 290.4 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 3178 | 307.6 | 140.8 | 327.3 | 122.2 | --- | --- | C3'endo | 0.386 |
| 1 | A5 | A | 3245 | 235.7 | 304.7 | 268.9 | 303.5 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 3351 | 92.5 | 269.7 | --- | --- | --- | --- | C3'endo | 0.0 |
| 1 | A5 | G | 3369 | 326.9 | 81.0 | 300.1 | 74.6 | 299.4 | 74.2 | C3'endo | 0.0 |
| 1 | A5 | A | 3376 | 129.0 | 334.0 | 102.7 | 289.4 | --- | --- | C3'endo | 0.459 |
| 1 | A7 | A | 64 | 286.9 | 337.6 | 328.9 | 336.0 | 23.3 | 320.5 | C3'endo | 0.592 |
| 1 | A7 | C | 73 | 8.6 | 105.2 | 12.8 | 79.1 | 31.7 | 7.1 | C3'endo | 0.0 |
| 1 | A8 | U | 86 | 325.1 | 74.6 | 314.9 | 82.4 | 301.2 | 55.2 | C3'endo | 0.0 |
| 1 | A8 | U | 113 | 268.2 | 29.6 | 295.1 | 60.6 | 353.6 | 102.7 | C3'endo | 0.0 |
| 1 | A8 | C | 151 | 303.3 | 137.7 | 320.0 | 112.9 | --- | --- | C3'endo | 0.592 |
| 1 | A2 | A | 67 | --- | --- | 296.2 | 127.2 | 312.4 | 68.3 | C3'endo | 0.0 |
| 1 | A2 | G | 279 | --- | --- | 154.3 | 314.4 | --- | --- | C3'endo | 0.0 |
| 1 | A2 | C | 1159 | --- | --- | 288.0 | 345.0 | 316.6 | 322.9 | C3'endo | 0.038 |
| 1 | A2 | A | 1244 | --- | --- | 16.4 | 172.1 | 74.6 | 182.1 | C3'endo | 0.0 |
| 1 | A2 | U | 1656 | --- | --- | 210.2 | 320.1 | --- | --- | C3'endo | 0.457 |
| 1 | A1 | G | 283 | --- | --- | 140.2 | 289.3 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 578 | --- | --- | 53.0 | 21.1 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | U | 874 | --- | --- | 276.9 | 68.1 | 305.4 | 123.8 | C3'endo | 0.0 |
| 1 | A1 | A | 913 | --- | --- | 351.0 | 84.1 | 353.2 | 23.5 | C3'endo | 0.334 |
| 1 | A1 | A | 1190 | --- | --- | 110.4 | 132.0 | --- | --- | C3'endo | 0.293 |
| 1 | A1 | A | 1200 | --- | --- | 148.0 | 48.3 | 108.7 | 52.1 | C3'endo | 0.549 |
| 1 | A1 | A | 1330 | --- | --- | 126.4 | 139.8 | 143.2 | 108.9 | C3'endo | 0.0 |
| 1 | A1 | U | 1569 | --- | --- | 134.3 | 303.6 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | C | 1582 | --- | --- | 264.0 | 171.9 | --- | --- | C3'endo | 0.0 |
| 1 | A1 | A | 2143 | --- | --- | 108.6 | 145.9 | 119.3 | 98.4 | C3'endo | 0.596 |
| 1 | A1 | C | 2560 | --- | --- | 299.1 | 295.7 | --- | --- | C3'endo | 0.109 |
| 1 | A1 | A | 2703 | --- | --- | 281.1 | 29.6 | --- | --- | C3'endo | 0.26 |
| 1 | A1 | G | 2874 | --- | --- | 328.9 | 165.7 | 333.4 | 164.4 | C3'endo | 0.866 |
| 1 | A1 | C | 3120 | --- | --- | 352.2 | 155.5 | 348.5 | 107.1 | C3'endo | 0.157 |
| 1 | A3 | A | 11 | --- | --- | 252.8 | 151.8 | --- | --- | C3'endo | 0.138 |
| 1 | A6 | A | 67 | --- | --- | 298.3 | 134.0 | 315.5 | 60.5 | C3'endo | 0.0 |
| 1 | A6 | G | 496 | --- | --- | 241.9 | 283.5 | 298.0 | 341.5 | C3'endo | 0.0 |
| 1 | A6 | U | 608 | --- | --- | 345.9 | 107.8 | 80.4 | 103.1 | C3'endo | 0.508 |
| 1 | A6 | G | 652 | --- | --- | 236.9 | 291.6 | --- | --- | C3'endo | 0.0 |
| 1 | A6 | C | 1159 | --- | --- | 283.2 | 343.5 | 316.0 | 320.2 | C3'endo | 0.0 |
| 1 | A6 | A | 1244 | --- | --- | 2.1 | 171.4 | 63.0 | 171.4 | C3'endo | 0.0 |
| 1 | A6 | U | 1656 | --- | --- | 212.9 | 341.9 | --- | --- | C3'endo | 0.034 |
| 1 | A6 | U | 1657 | --- | --- | 285.8 | 23.8 | 334.4 | 299.2 | C3'endo | 0.0 |
| 1 | A5 | G | 283 | --- | --- | 142.1 | 289.8 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | C | 546 | --- | --- | 224.4 | 83.4 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | A | 578 | --- | --- | 54.7 | 16.7 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | U | 874 | --- | --- | 277.6 | 68.4 | 303.9 | 124.3 | C3'endo | 0.0 |
| 1 | A5 | A | 913 | --- | --- | 348.7 | 85.9 | 352.0 | 23.3 | C3'endo | 0.258 |
| 1 | A5 | U | 1015 | --- | --- | 145.4 | 113.3 | 197.7 | 52.3 | C3'endo | 0.0 |
| 1 | A5 | A | 1190 | --- | --- | 108.4 | 131.4 | --- | --- | C3'endo | 0.3 |
| 1 | A5 | A | 1200 | --- | --- | 152.9 | 53.7 | 112.9 | 58.6 | C3'endo | 0.467 |
| 1 | A5 | A | 1330 | --- | --- | 133.2 | 140.3 | 140.7 | 112.1 | C3'endo | 0.0 |
| 1 | A5 | A | 2143 | --- | --- | 110.1 | 142.1 | 118.1 | 97.7 | C3'endo | 0.689 |
| 1 | A5 | A | 2397 | --- | --- | 279.1 | 33.7 | --- | --- | C3'endo | 0.0 |
| 1 | A5 | C | 2560 | --- | --- | 293.2 | 293.1 | --- | --- | C3'endo | 0.356 |
| 1 | A5 | U | 2570 | --- | --- | 113.5 | 117.0 | 122.4 | 52.7 | C3'endo | 0.0 |
| 1 | A5 | A | 2703 | --- | --- | 281.5 | 30.6 | --- | --- | C3'endo | 0.042 |
| 1 | A5 | G | 2874 | --- | --- | 322.3 | 162.0 | 343.4 | 167.9 | C3'endo | 0.463 |
| 1 | A5 | C | 3120 | --- | --- | 351.5 | 156.7 | 350.5 | 107.2 | C3'endo | 0.347 |
| 1 | A2 | A | 68 | --- | --- | --- | --- | 71.6 | 339.6 | C3'endo | 0.0 |
| 1 | A2 | U | 75 | --- | --- | --- | --- | 20.3 | 187.6 | C3'endo | 0.0 |
| 1 | A2 | A | 138 | --- | --- | --- | --- | 50.8 | 187.8 | C3'endo | 0.0 |
| 1 | A2 | U | 193 | --- | --- | --- | --- | 91.7 | 105.9 | C3'endo | 0.0 |
| 1 | A2 | A | 359 | --- | --- | --- | --- | 94.5 | 339.2 | C3'endo | 0.0 |
| 1 | A2 | G | 403 | 281.2 | 55.4 | --- | --- | 336.8 | 318.8 | C3'endo | 0.0 |
| 1 | A2 | U | 440 | 283.9 | 332.6 | --- | --- | 325.2 | 61.7 | C3'endo | 0.41 |
| 1 | A2 | U | 476 | --- | --- | --- | --- | 264.7 | 32.0 | C3'endo | 0.599 |
| 1 | A2 | U | 493 | 97.3 | 285.0 | --- | --- | 68.8 | 162.2 | C3'endo | 0.0 |
| 1 | A2 | U | 718 | --- | --- | --- | --- | 35.5 | 138.6 | C3'endo | 0.0 |
| 1 | A2 | A | 788 | --- | --- | --- | --- | 257.2 | 38.9 | C3'endo | 0.341 |
| 1 | A2 | G | 876 | --- | --- | --- | --- | 28.7 | 194.0 | C3'endo | 0.0 |
| 1 | A2 | U | 1535 | 233.8 | 53.9 | --- | --- | 174.3 | 69.0 | C3'endo | 0.0 |
| 1 | A1 | A | 49 | 322.7 | 15.5 | --- | --- | 285.8 | 83.5 | C3'endo | 0.0 |
| 1 | A1 | U | 252 | 323.3 | 358.7 | --- | --- | 303.6 | 73.6 | C3'endo | 0.0 |
| 1 | A1 | C | 546 | --- | --- | --- | --- | 164.2 | 20.8 | C3'endo | 0.0 |
| 1 | A1 | U | 879 | 294.9 | 44.2 | --- | --- | 148.3 | 30.8 | C3'endo | 0.0 |
| 1 | A1 | A | 883 | 301.5 | 105.4 | --- | --- | 313.0 | 118.1 | C3'endo | 0.0 |
| 1 | A1 | G | 953 | --- | --- | --- | --- | 178.4 | 36.5 | C3'endo | 0.425 |
| 1 | A1 | C | 959 | 358.3 | 55.5 | --- | --- | 338.0 | 33.0 | C3'endo | 0.0 |
| 1 | A1 | A | 1302 | --- | --- | --- | --- | 95.3 | 134.0 | C3'endo | 0.282 |
| 1 | A1 | G | 1349 | --- | --- | --- | --- | 53.8 | 97.6 | C3'endo | 0.0 |
| 1 | A1 | A | 1386 | 254.1 | 22.9 | --- | --- | 329.4 | 119.8 | C3'endo | 0.0 |
| 1 | A1 | C | 1628 | --- | --- | --- | --- | 189.9 | 334.1 | C3'endo | 0.37 |
| 1 | A1 | U | 1717 | --- | --- | --- | --- | 347.2 | 182.3 | C3'endo | 0.0 |
| 1 | A1 | C | 2114 | --- | --- | --- | --- | 125.6 | 17.5 | C3'endo | 0.0 |
| 1 | A1 | U | 2725 | --- | --- | --- | --- | 187.2 | 336.2 | C3'endo | 0.495 |
| 1 | A1 | A | 2845 | --- | --- | --- | --- | 336.4 | 305.4 | C3'endo | 0.0 |
| 1 | A1 | U | 2846 | --- | --- | --- | --- | 290.1 | 11.4 | C3'endo | 0.208 |
| 1 | A1 | G | 2898 | 60.0 | 31.1 | --- | --- | 37.4 | 338.1 | C3'endo | 0.0 |
| 1 | A1 | C | 2899 | --- | --- | --- | --- | 121.8 | 133.6 | C3'endo | 0.0 |
| 1 | A1 | C | 3181 | --- | --- | --- | --- | 297.0 | 184.0 | C3'endo | 0.0 |
| 1 | A1 | C | 3206 | 117.1 | 36.4 | --- | --- | 201.9 | 38.0 | C3'endo | 0.41 |
| 1 | A1 | A | 3316 | --- | --- | --- | --- | 178.3 | 83.5 | C3'endo | 0.0 |
| 1 | A1 | G | 3353 | 207.0 | 308.8 | --- | --- | 165.4 | 22.6 | C3'endo | 0.0 |
| 1 | A4 | U | 82 | --- | --- | --- | --- | 72.2 | 163.3 | C3'endo | 0.0 |
| 1 | A6 | A | 138 | --- | --- | --- | --- | 76.7 | 180.8 | C3'endo | 0.0 |
| 1 | A6 | U | 193 | --- | --- | --- | --- | 94.5 | 100.2 | C3'endo | 0.0 |
| 1 | A6 | A | 359 | --- | --- | --- | --- | 96.8 | 341.1 | C3'endo | 0.0 |
| 1 | A6 | G | 403 | 283.6 | 61.4 | --- | --- | 339.7 | 317.7 | C3'endo | 0.01 |
| 1 | A6 | U | 440 | 280.5 | 339.0 | --- | --- | 326.9 | 61.2 | C3'endo | 0.449 |
| 1 | A6 | U | 476 | --- | --- | --- | --- | 265.8 | 38.5 | C3'endo | 0.213 |
| 1 | A6 | G | 488 | --- | --- | --- | --- | 300.5 | 161.1 | C3'endo | 0.0 |
| 1 | A6 | C | 491 | --- | --- | --- | --- | 269.6 | 337.5 | C3'endo | 0.421 |
| 1 | A6 | U | 493 | --- | --- | --- | --- | 27.7 | 159.3 | C3'endo | 0.0 |
| 1 | A6 | G | 540 | --- | --- | --- | --- | 196.3 | 41.5 | C3'endo | 0.0 |
| 1 | A6 | C | 682 | --- | --- | --- | --- | 75.2 | 176.4 | C3'endo | 0.0 |
| 1 | A6 | G | 876 | --- | --- | --- | --- | 26.3 | 180.7 | C3'endo | 0.0 |
| 1 | A6 | A | 1227 | 225.6 | 34.2 | --- | --- | 153.6 | 336.9 | C3'endo | 0.33 |
| 1 | A6 | U | 1535 | 243.6 | 50.5 | --- | --- | 175.6 | 73.1 | C3'endo | 0.0 |
| 1 | A6 | C | 1537 | 304.8 | 82.9 | --- | --- | 278.6 | 62.0 | C3'endo | 0.0 |
| 1 | A6 | C | 1615 | --- | --- | --- | --- | 186.0 | 69.9 | C3'endo | 0.271 |
| 1 | A5 | A | 49 | 323.3 | 17.1 | --- | --- | 284.9 | 84.3 | C3'endo | 0.0 |
| 1 | A5 | U | 620 | 296.4 | 42.7 | --- | --- | 313.0 | 33.0 | C3'endo | 0.0 |
| 1 | A5 | U | 879 | 295.0 | 43.0 | --- | --- | 142.6 | 26.1 | C3'endo | 0.0 |
| 1 | A5 | A | 883 | 298.8 | 112.3 | --- | --- | 311.8 | 117.5 | C3'endo | 0.882 |
| 1 | A5 | G | 953 | --- | --- | --- | --- | 176.6 | 36.5 | C3'endo | 0.541 |
| 1 | A5 | A | 1302 | --- | --- | --- | --- | 97.2 | 136.6 | C3'endo | 0.257 |
| 1 | A5 | U | 1348 | --- | --- | --- | --- | 140.1 | 50.2 | C3'endo | 0.0 |
| 1 | A5 | A | 1386 | --- | --- | --- | --- | 328.4 | 120.9 | C3'endo | 0.0 |
| 1 | A5 | U | 1555 | --- | --- | --- | --- | 106.9 | 173.5 | C3'endo | 0.0 |
| 1 | A5 | C | 1628 | --- | --- | --- | --- | 185.2 | 342.3 | C3'endo | 0.266 |
| 1 | A5 | A | 1932 | --- | --- | --- | --- | 347.2 | 297.0 | C3'endo | 0.097 |
| 1 | A5 | C | 2114 | --- | --- | --- | --- | 124.1 | 21.3 | C3'endo | 0.0 |
| 1 | A5 | C | 2552 | --- | --- | --- | --- | 342.0 | 300.0 | C3'endo | 0.0 |
| 1 | A5 | U | 2725 | --- | --- | --- | --- | 198.9 | 335.3 | C3'endo | 0.567 |
| 1 | A5 | G | 2898 | 60.9 | 30.0 | --- | --- | 37.1 | 340.5 | C3'endo | 0.0 |
| 1 | A5 | C | 2899 | --- | --- | --- | --- | 121.8 | 130.1 | C3'endo | 0.0 |
| 1 | A5 | C | 3206 | 115.3 | 32.0 | --- | --- | 199.3 | 36.4 | C3'endo | 0.313 |
| 1 | A5 | U | 3341 | --- | --- | --- | --- | 9.5 | 101.0 | C3'endo | 0.0 |
| 1 | A2 | A | 47 | 11.7 | 58.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 56 | 313.8 | 159.0 | 58.7 | 129.3 | --- | --- | C2'endo | 0.282 |
| 1 | A2 | A | 72 | 241.8 | 197.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | G | 115 | 338.4 | 230.0 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | A2 | G | 127 | 281.1 | 287.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 133 | 156.9 | 49.1 | 141.8 | 189.6 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | C | 136 | 147.7 | 88.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 137 | 150.9 | 260.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 141 | 136.5 | 98.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 178 | 89.4 | 126.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | G | 322 | 262.6 | 171.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 468 | 331.1 | 228.4 | 337.2 | 194.1 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 506 | 272.7 | 198.1 | 353.3 | 206.0 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 541 | 71.4 | 250.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 542 | 305.7 | 223.8 | 309.1 | 216.2 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 545 | 337.2 | 169.4 | 6.3 | 165.7 | 338.3 | 218.2 | C2'endo | 0.0 |
| 1 | A2 | U | 639 | 34.2 | 74.0 | 67.0 | 84.1 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | C | 696 | 31.2 | 94.0 | 297.1 | 115.7 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 727 | 154.1 | 265.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | G | 732 | 31.8 | 101.1 | 316.6 | 200.2 | 335.8 | 215.1 | C2'endo | 0.0 |
| 1 | A2 | U | 782 | 168.0 | 45.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 814 | 298.4 | 182.2 | 325.0 | 154.5 | --- | --- | C2'endo | 0.11 |
| 1 | A2 | U | 959 | 18.7 | 205.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 1026 | 52.9 | 38.0 | 48.1 | 12.2 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 1059 | 20.9 | 223.3 | 78.3 | 208.3 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | C | 1096 | 99.7 | 133.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | G | 1100 | 129.8 | 181.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | C | 1158 | 328.5 | 187.3 | 324.9 | 192.7 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 1193 | 51.8 | 359.5 | --- | --- | --- | --- | C2'endo | 0.729 |
| 1 | A2 | G | 1200 | 112.6 | 79.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 1217 | 107.5 | 354.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 1227 | 200.7 | 30.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | G | 1228 | 6.6 | 23.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 1314 | 10.7 | 57.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 1346 | 321.8 | 137.6 | --- | --- | --- | --- | C2'endo | 0.209 |
| 1 | A2 | U | 1370 | 339.9 | 44.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 1427 | 266.5 | 358.0 | 299.0 | 33.0 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | C | 1490 | 20.3 | 99.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 1558 | 34.4 | 43.4 | 95.2 | 9.5 | 91.2 | 22.0 | C2'endo | 0.527 |
| 1 | A1 | U | 117 | 348.0 | 212.4 | 48.0 | 170.1 | 78.8 | 132.0 | C2'endo | 0.179 |
| 1 | A1 | C | 135 | 295.5 | 357.4 | 299.8 | 341.9 | 280.5 | 8.2 | C2'endo | 0.0 |
| 1 | A1 | U | 305 | 285.6 | 165.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 352 | 298.0 | 177.7 | 292.3 | 148.2 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 376 | 157.5 | 41.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 398 | 19.8 | 71.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 401 | 221.9 | 19.9 | 205.6 | 348.9 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 647 | 252.6 | 231.0 | --- | --- | --- | --- | C2'endo | 0.075 |
| 1 | A1 | A | 716 | 285.3 | 259.0 | 281.1 | 204.3 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 1028 | 34.7 | 56.2 | 45.3 | 11.2 | 10.5 | 19.8 | C2'endo | 0.218 |
| 1 | A1 | G | 1097 | 224.7 | 4.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 1116 | 100.4 | 225.8 | --- | --- | --- | --- | C2'endo | 0.017 |
| 1 | A1 | U | 1181 | 340.2 | 25.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 1221 | 348.7 | 25.7 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | A1 | A | 1245 | 133.7 | 349.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 1253 | 116.5 | 152.8 | 157.9 | 116.8 | --- | --- | C2'endo | 0.01 |
| 1 | A1 | G | 1306 | 57.5 | 253.2 | --- | --- | --- | --- | C2'endo | 0.626 |
| 1 | A1 | A | 1433 | 327.4 | 244.8 | --- | --- | --- | --- | C2'endo | 0.01 |
| 1 | A1 | A | 1588 | 224.7 | 39.5 | 274.6 | 343.9 | --- | --- | C2'endo | 0.433 |
| 1 | A1 | U | 1630 | 322.1 | 192.7 | 339.5 | 206.2 | --- | --- | C2'endo | 0.444 |
| 1 | A1 | A | 1642 | 354.6 | 245.4 | 51.3 | 222.5 | --- | --- | C2'endo | 0.01 |
| 1 | A1 | A | 1715 | 99.0 | 135.9 | --- | --- | --- | --- | C2'endo | 0.38 |
| 1 | A1 | U | 1724 | 268.1 | 168.9 | 291.7 | 133.9 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 1761 | 152.5 | 257.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 1841 | 311.3 | 216.3 | 315.1 | 207.3 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 1846 | 289.6 | 282.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2116 | 246.2 | 278.0 | 290.1 | 271.3 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2256 | 108.5 | 61.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2273 | 150.5 | 70.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2281 | 38.5 | 210.5 | 54.2 | 230.7 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2283 | 117.6 | 93.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2307 | 139.1 | 357.7 | 152.7 | 320.6 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2313 | 274.1 | 46.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2335 | 298.3 | 150.6 | --- | --- | --- | --- | C2'endo | 0.111 |
| 1 | A1 | A | 2373 | 148.5 | 31.9 | 159.5 | 331.5 | --- | --- | C2'endo | 0.048 |
| 1 | A1 | G | 2418 | 49.8 | 216.1 | 16.4 | 178.4 | 342.0 | 70.5 | C2'endo | 0.0 |
| 1 | A1 | U | 2514 | 78.4 | 230.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 2538 | 264.7 | 225.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 2539 | 268.7 | 348.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2540 | 313.0 | 130.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 2542 | 317.9 | 149.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2549 | 294.5 | 230.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2580 | 50.7 | 350.8 | --- | --- | --- | --- | C2'endo | 0.439 |
| 1 | A1 | A | 2593 | 284.9 | 356.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 2627 | 108.2 | 227.9 | --- | --- | --- | --- | C2'endo | 0.334 |
| 1 | A1 | A | 2635 | 64.3 | 84.1 | --- | --- | --- | --- | C2'endo | 0.542 |
| 1 | A1 | G | 2651 | 214.6 | 30.1 | --- | --- | --- | --- | C2'endo | 0.118 |
| 1 | A1 | U | 2688 | 311.5 | 145.0 | --- | --- | --- | --- | C2'endo | 0.24 |
| 1 | A1 | G | 2796 | 117.9 | 59.0 | 146.7 | 23.4 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2802 | 26.0 | 192.5 | 70.0 | 199.9 | --- | --- | C2'endo | 0.01 |
| 1 | A1 | C | 2983 | 75.6 | 254.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 3056 | 20.5 | 186.9 | 15.3 | 156.5 | 4.4 | 125.8 | C2'endo | 0.0 |
| 1 | A1 | C | 3093 | 13.2 | 226.8 | --- | --- | --- | --- | C2'endo | 0.062 |
| 1 | A1 | A | 3141 | 217.4 | 359.8 | --- | --- | --- | --- | C2'endo | 0.513 |
| 1 | A1 | C | 3143 | 113.0 | 37.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 3157 | 71.6 | 20.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 3186 | 349.6 | 55.8 | 25.2 | 24.1 | --- | --- | C2'endo | 0.451 |
| 1 | A1 | G | 3208 | 65.4 | 80.2 | 90.5 | 46.2 | --- | --- | C2'endo | 0.038 |
| 1 | A1 | C | 3217 | 44.9 | 253.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 3219 | 167.6 | 47.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 3246 | 153.8 | 28.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 3341 | 39.1 | 223.2 | 52.5 | 221.9 | 31.1 | 226.3 | C2'endo | 0.0 |
| 1 | A1 | U | 3382 | 232.3 | 17.1 | 326.2 | 324.1 | --- | --- | C2'endo | 0.0 |
| 1 | A4 | U | 34 | 108.7 | 194.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A4 | C | 62 | 283.6 | 19.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A4 | G | 87 | 119.3 | 154.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A4 | C | 106 | 113.2 | 132.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 47 | 6.4 | 62.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 56 | 309.6 | 167.0 | 52.7 | 131.3 | --- | --- | C2'endo | 0.375 |
| 1 | A6 | G | 115 | 342.5 | 226.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | G | 127 | 290.0 | 290.2 | --- | --- | --- | --- | C2'endo | 0.033 |
| 1 | A6 | A | 217 | 31.5 | 251.9 | 55.6 | 207.7 | 50.4 | 213.7 | C2'endo | 0.0 |
| 1 | A6 | G | 322 | 262.5 | 171.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | C | 455 | 142.4 | 290.6 | --- | --- | --- | --- | C2'endo | 0.299 |
| 1 | A6 | A | 468 | 330.5 | 223.4 | 334.1 | 192.0 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | C | 489 | 25.7 | 244.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 506 | 258.1 | 288.3 | 329.0 | 275.5 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 545 | 317.1 | 175.4 | 357.8 | 167.9 | 333.1 | 216.4 | C2'endo | 0.118 |
| 1 | A6 | U | 639 | 29.7 | 71.5 | 54.0 | 89.4 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | C | 696 | 84.5 | 40.6 | 139.1 | 50.1 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 721 | 97.4 | 228.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | G | 765 | 323.3 | 134.2 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 780 | 138.7 | 68.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 782 | 208.1 | 20.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 814 | 285.9 | 189.7 | 317.2 | 160.6 | 320.6 | 128.2 | C2'endo | 0.01 |
| 1 | A6 | A | 1026 | 54.8 | 32.2 | 51.0 | 7.6 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | C | 1096 | 97.4 | 126.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | G | 1100 | 125.8 | 175.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | C | 1158 | 340.6 | 178.7 | 324.5 | 195.0 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 1193 | 44.7 | 9.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | G | 1200 | 111.7 | 75.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 1217 | 107.2 | 346.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 1314 | 12.0 | 63.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 1362 | 6.8 | 252.3 | 34.9 | 199.4 | 351.4 | 138.2 | C2'endo | 0.048 |
| 1 | A6 | U | 1363 | 357.8 | 43.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | C | 1490 | 28.0 | 87.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 1558 | 28.5 | 46.2 | 94.7 | 16.3 | --- | --- | C2'endo | 0.176 |
| 1 | A5 | U | 117 | 348.2 | 208.5 | 47.9 | 167.5 | 78.5 | 131.1 | C2'endo | 0.213 |
| 1 | A5 | U | 169 | 257.8 | 190.3 | --- | --- | --- | --- | C2'endo | 0.202 |
| 1 | A5 | U | 305 | 282.4 | 165.6 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 350 | 144.7 | 282.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 352 | 305.4 | 173.9 | 293.3 | 146.2 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 376 | 155.0 | 43.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 398 | 26.3 | 58.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | U | 401 | 225.3 | 18.6 | 205.0 | 350.0 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 439 | 131.5 | 81.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 647 | 255.2 | 229.2 | --- | --- | --- | --- | C2'endo | 0.33 |
| 1 | A5 | A | 716 | 273.5 | 256.2 | 270.6 | 204.0 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 765 | 344.1 | 35.1 | --- | --- | --- | --- | C2'endo | 0.16 |
| 1 | A5 | C | 1017 | 288.8 | 269.5 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 1116 | 102.3 | 228.1 | --- | --- | --- | --- | C2'endo | 0.167 |
| 1 | A5 | U | 1181 | 331.5 | 39.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 1192 | 304.4 | 273.9 | 331.3 | 241.1 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 1245 | 111.6 | 36.7 | 113.1 | 353.2 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 1306 | 59.4 | 249.1 | --- | --- | --- | --- | C2'endo | 0.635 |
| 1 | A5 | A | 1352 | 263.9 | 229.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 1433 | 332.2 | 243.4 | --- | --- | --- | --- | C2'endo | 0.016 |
| 1 | A5 | C | 1556 | 60.4 | 232.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 1588 | 231.9 | 32.7 | 279.9 | 337.9 | --- | --- | C2'endo | 0.511 |
| 1 | A5 | U | 1630 | 319.0 | 194.2 | 335.2 | 206.0 | 345.6 | 254.2 | C2'endo | 0.153 |
| 1 | A5 | A | 1642 | 335.6 | 244.7 | 38.9 | 228.4 | --- | --- | C2'endo | 0.184 |
| 1 | A5 | U | 1724 | 253.9 | 183.6 | 292.7 | 135.9 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 1841 | 297.0 | 225.1 | 299.2 | 213.3 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 1842 | 245.2 | 285.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 1847 | 150.3 | 273.6 | --- | --- | --- | --- | C2'endo | 0.24 |
| 1 | A5 | G | 2116 | 249.4 | 278.1 | --- | --- | --- | --- | C2'endo | 0.07 |
| 1 | A5 | U | 2205 | 38.6 | 248.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 2279 | 240.7 | 43.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 2281 | 42.9 | 210.5 | 56.0 | 230.3 | --- | --- | C2'endo | 0.016 |
| 1 | A5 | G | 2307 | 138.3 | 349.9 | 147.8 | 317.4 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 2335 | 297.9 | 149.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 2373 | 152.9 | 42.2 | 162.3 | 336.8 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 2401 | 106.5 | 208.1 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | U | 2514 | 69.4 | 240.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 2539 | 241.2 | 19.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | U | 2541 | 113.1 | 188.3 | --- | --- | --- | --- | C2'endo | 0.488 |
| 1 | A5 | G | 2549 | 264.4 | 232.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 2585 | 273.0 | 188.7 | 290.5 | 166.9 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 2593 | 288.8 | 358.3 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 2627 | 109.5 | 225.4 | --- | --- | --- | --- | C2'endo | 0.17 |
| 1 | A5 | A | 2635 | 57.1 | 91.5 | --- | --- | --- | --- | C2'endo | 0.72 |
| 1 | A5 | U | 2688 | 313.6 | 141.7 | --- | --- | --- | --- | C2'endo | 0.177 |
| 1 | A5 | G | 2796 | 118.6 | 63.5 | 149.6 | 23.9 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | U | 3056 | 23.1 | 187.2 | 16.9 | 156.5 | 2.4 | 150.0 | C2'endo | 0.0 |
| 1 | A5 | A | 3141 | 212.7 | 6.0 | --- | --- | --- | --- | C2'endo | 0.199 |
| 1 | A5 | C | 3143 | 114.0 | 37.4 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 3186 | 352.3 | 52.2 | 25.9 | 22.3 | --- | --- | C2'endo | 0.446 |
| 1 | A5 | G | 3208 | 57.2 | 81.5 | 84.5 | 52.1 | --- | --- | C2'endo | 0.312 |
| 1 | A5 | G | 3219 | 171.0 | 46.8 | 159.2 | 64.5 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 3246 | 159.1 | 31.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 3274 | 180.3 | 29.9 | --- | --- | --- | --- | C2'endo | 0.418 |
| 1 | A5 | U | 3382 | 263.5 | 345.0 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A8 | U | 34 | 111.6 | 197.9 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A8 | G | 87 | 117.4 | 162.8 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A8 | C | 106 | 120.3 | 127.7 | --- | --- | --- | --- | C2'endo | 0.0 |
| 1 | A2 | A | 26 | --- | --- | 46.0 | 170.6 | 30.9 | 198.1 | C2'endo | 0.0 |
| 1 | A2 | A | 46 | --- | --- | 91.2 | 99.0 | 81.5 | 117.7 | C2'endo | 0.0 |
| 1 | A2 | U | 249 | --- | --- | 70.5 | 326.3 | 40.1 | 25.2 | C2'endo | 0.0 |
| 1 | A2 | U | 260 | --- | --- | 344.6 | 346.2 | 14.0 | 9.5 | C2'endo | 0.575 |
| 1 | A2 | A | 265 | --- | --- | 271.5 | 204.0 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 721 | --- | --- | 320.1 | 4.3 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | C | 731 | --- | --- | 160.0 | 189.0 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 1305 | --- | --- | 123.2 | 323.6 | --- | --- | C2'endo | 0.696 |
| 1 | A2 | U | 1362 | --- | --- | 39.2 | 207.1 | --- | --- | C2'endo | 0.01 |
| 1 | A2 | U | 1363 | --- | --- | 161.0 | 275.9 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 1432 | --- | --- | 45.3 | 80.6 | 89.3 | 108.0 | C2'endo | 0.039 |
| 1 | A2 | A | 1446 | --- | --- | 283.2 | 186.2 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 40 | --- | --- | 312.4 | 254.3 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 66 | --- | --- | 270.3 | 235.6 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 109 | --- | --- | 82.2 | 153.4 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 218 | --- | --- | 53.9 | 240.4 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 221 | --- | --- | 271.9 | 216.7 | --- | --- | C2'endo | 0.324 |
| 1 | A1 | A | 611 | --- | --- | 73.8 | 129.0 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 648 | --- | --- | 61.6 | 54.0 | --- | --- | C2'endo | 0.076 |
| 1 | A1 | A | 691 | --- | --- | 290.0 | 321.9 | 274.4 | 357.8 | C2'endo | 0.0 |
| 1 | A1 | A | 705 | --- | --- | 61.0 | 145.9 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 921 | --- | --- | 259.7 | 306.6 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 1103 | --- | --- | 65.7 | 338.2 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 1160 | --- | --- | 169.5 | 200.1 | --- | --- | C2'endo | 0.016 |
| 1 | A1 | C | 1192 | --- | --- | 314.1 | 252.2 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 1208 | --- | --- | 18.5 | 156.1 | 354.8 | 94.6 | C2'endo | 0.032 |
| 1 | A1 | U | 1455 | --- | --- | 268.5 | 264.0 | --- | --- | C2'endo | 0.01 |
| 1 | A1 | G | 1507 | --- | --- | 278.0 | 286.1 | --- | --- | C2'endo | 0.162 |
| 1 | A1 | A | 1559 | --- | --- | 274.1 | 273.4 | --- | --- | C2'endo | 0.436 |
| 1 | A1 | U | 1568 | --- | --- | 269.6 | 17.4 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2158 | --- | --- | 156.6 | 65.6 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | C | 2374 | --- | --- | 50.7 | 124.4 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2375 | --- | --- | 51.8 | 150.7 | 60.8 | 120.9 | C2'endo | 0.0 |
| 1 | A1 | C | 2444 | --- | --- | 175.7 | 297.6 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2502 | --- | --- | 172.3 | 275.7 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 2523 | --- | --- | 327.8 | 234.7 | 317.5 | 258.8 | C2'endo | 0.0 |
| 1 | A1 | A | 2561 | --- | --- | 40.9 | 186.6 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 2571 | --- | --- | 65.0 | 190.3 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2586 | --- | --- | 34.9 | 229.2 | 345.2 | 189.4 | C2'endo | 0.0 |
| 1 | A1 | A | 2689 | --- | --- | 149.6 | 53.5 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 2714 | --- | --- | 38.7 | 64.3 | 32.2 | 55.3 | C2'endo | 0.0 |
| 1 | A1 | G | 2754 | --- | --- | 218.2 | 346.2 | --- | --- | C2'endo | 0.01 |
| 1 | A1 | U | 2996 | --- | --- | 179.3 | 343.9 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 3011 | --- | --- | 87.0 | 138.6 | 57.7 | 151.1 | C2'endo | 0.499 |
| 1 | A1 | U | 3078 | --- | --- | 252.5 | 9.8 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 3155 | --- | --- | 120.1 | 322.9 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | U | 3156 | --- | --- | 305.3 | 185.8 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | A | 3243 | --- | --- | 38.7 | 232.1 | 42.8 | 182.3 | C2'endo | 0.0 |
| 1 | A1 | U | 3259 | --- | --- | 47.2 | 75.2 | 52.0 | 23.7 | C2'endo | 0.0 |
| 1 | A1 | U | 3355 | --- | --- | 329.3 | 249.9 | --- | --- | C2'endo | 0.0 |
| 1 | A1 | G | 3377 | --- | --- | 45.3 | 238.7 | --- | --- | C2'endo | 0.674 |
| 1 | A3 | A | 13 | --- | --- | 182.7 | 290.2 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 26 | --- | --- | 46.0 | 165.2 | 26.1 | 197.2 | C2'endo | 0.0 |
| 1 | A6 | U | 260 | --- | --- | 346.6 | 348.6 | 7.1 | 21.4 | C2'endo | 0.0 |
| 1 | A6 | A | 265 | --- | --- | 264.7 | 203.6 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 494 | --- | --- | 158.8 | 197.5 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | A | 542 | --- | --- | 309.2 | 224.7 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | N | 669 | --- | --- | 169.3 | 204.7 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | G | 720 | --- | --- | 290.7 | 114.4 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 742 | --- | --- | 320.4 | 245.1 | --- | --- | C2'endo | 0.0 |
| 1 | A6 | U | 779 | --- | --- | 85.1 | 321.5 | --- | --- | C2'endo | 0.117 |
| 1 | A6 | U | 794 | --- | --- | 252.1 | 335.8 | 236.1 | 20.7 | C2'endo | 0.0 |
| 1 | A6 | U | 1058 | --- | --- | 292.6 | 159.4 | 306.4 | 235.6 | C2'endo | 0.0 |
| 1 | A6 | U | 1305 | --- | --- | 128.2 | 314.5 | --- | --- | C2'endo | 0.119 |
| 1 | A6 | U | 1370 | --- | --- | 277.2 | 115.6 | --- | --- | C2'endo | 0.01 |
| 1 | A6 | U | 1432 | --- | --- | 38.2 | 84.3 | --- | --- | C2'endo | 0.14 |
| 1 | A6 | A | 1446 | --- | --- | 292.1 | 192.5 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 40 | --- | --- | 311.7 | 254.9 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 66 | --- | --- | 271.3 | 234.8 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 109 | --- | --- | 82.6 | 152.8 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 116 | --- | --- | 155.0 | 184.5 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 135 | --- | --- | 312.1 | 337.4 | 271.3 | 7.8 | C2'endo | 0.0 |
| 1 | A5 | A | 219 | --- | --- | 132.0 | 199.0 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 221 | --- | --- | 271.3 | 216.7 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 611 | --- | --- | 68.8 | 131.0 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 648 | --- | --- | 61.4 | 48.5 | --- | --- | C2'endo | 0.114 |
| 1 | A5 | A | 691 | --- | --- | 289.3 | 325.3 | 275.0 | 356.1 | C2'endo | 0.064 |
| 1 | A5 | A | 705 | --- | --- | 62.8 | 140.9 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 921 | --- | --- | 254.5 | 309.5 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | U | 1095 | --- | --- | 81.6 | 85.9 | 95.8 | 123.0 | C2'endo | 0.0 |
| 1 | A5 | C | 1160 | --- | --- | 172.9 | 201.2 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | U | 1208 | --- | --- | 16.9 | 150.2 | --- | --- | C2'endo | 0.251 |
| 1 | A5 | U | 1455 | --- | --- | 268.4 | 261.8 | --- | --- | C2'endo | 0.108 |
| 1 | A5 | G | 1507 | --- | --- | 276.0 | 289.3 | --- | --- | C2'endo | 0.378 |
| 1 | A5 | A | 2158 | --- | --- | 157.9 | 64.1 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 2256 | --- | --- | 92.5 | 80.5 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | C | 2374 | --- | --- | 48.4 | 124.9 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 2375 | --- | --- | 51.3 | 150.7 | 57.2 | 122.6 | C2'endo | 0.0 |
| 1 | A5 | U | 2542 | --- | --- | 293.7 | 148.8 | --- | --- | C2'endo | 0.157 |
| 1 | A5 | A | 2561 | --- | --- | 43.9 | 189.4 | --- | --- | C2'endo | 0.359 |
| 1 | A5 | G | 2586 | --- | --- | 33.0 | 226.2 | 339.7 | 191.8 | C2'endo | 0.096 |
| 1 | A5 | A | 2689 | --- | --- | 154.0 | 52.1 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | G | 2714 | --- | --- | 42.4 | 70.6 | 39.4 | 31.5 | C2'endo | 0.0 |
| 1 | A5 | G | 2754 | --- | --- | 216.3 | 351.9 | --- | --- | C2'endo | 0.386 |
| 1 | A5 | A | 2802 | --- | --- | 70.1 | 198.7 | --- | --- | C2'endo | 0.043 |
| 1 | A5 | U | 2996 | --- | --- | 183.0 | 338.5 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 3011 | --- | --- | 82.7 | 139.3 | 58.6 | 151.2 | C2'endo | 0.562 |
| 1 | A5 | U | 3078 | --- | --- | 262.8 | 11.6 | --- | --- | C2'endo | 0.0 |
| 1 | A5 | A | 3243 | --- | --- | 36.7 | 234.3 | 44.2 | 184.7 | C2'endo | 0.043 |
| 1 | A5 | U | 3259 | --- | --- | 45.6 | 78.8 | 51.7 | 28.4 | C2'endo | 0.0 |
| 1 | A5 | U | 3354 | --- | --- | 251.6 | 17.2 | --- | --- | C2'endo | 0.0 |
| 1 | A8 | C | 84 | --- | --- | 271.6 | 35.4 | --- | --- | C2'endo | 0.0 |
| 1 | A2 | U | 66 | --- | --- | --- | --- | 25.4 | 209.5 | C2'endo | 0.018 |
| 1 | A2 | U | 159 | --- | --- | --- | --- | 45.2 | 161.4 | C2'endo | 0.0 |
| 1 | A2 | G | 199 | --- | --- | --- | --- | 277.8 | 243.0 | C2'endo | 0.0 |
| 1 | A2 | U | 313 | --- | --- | --- | --- | 347.6 | 330.0 | C2'endo | 0.302 |
| 1 | A2 | C | 321 | --- | --- | --- | --- | 71.6 | 63.8 | C2'endo | 0.0 |
| 1 | A2 | G | 459 | --- | --- | --- | --- | 276.2 | 34.6 | C2'endo | 0.21 |
| 1 | A2 | C | 554 | --- | --- | --- | --- | 86.8 | 137.2 | C2'endo | 0.692 |
| 1 | A2 | A | 580 | 286.9 | 273.1 | --- | --- | 327.4 | 161.2 | C2'endo | 0.0 |
| 1 | A2 | A | 606 | --- | --- | --- | --- | 88.9 | 53.8 | C2'endo | 0.212 |
| 1 | A2 | U | 813 | --- | --- | --- | --- | 335.4 | 305.4 | C2'endo | 0.0 |
| 1 | A2 | U | 1058 | 145.5 | 262.0 | --- | --- | 77.2 | 147.4 | C2'endo | 0.0 |
| 1 | A2 | U | 1185 | --- | --- | --- | --- | 287.1 | 258.8 | C2'endo | 0.0 |
| 1 | A2 | G | 1243 | --- | --- | --- | --- | 359.3 | 19.6 | C2'endo | 0.0 |
| 1 | A2 | G | 1245 | --- | --- | --- | --- | 294.7 | 41.1 | C2'endo | 0.0 |
| 1 | A2 | U | 1285 | --- | --- | --- | --- | 4.5 | 11.4 | C2'endo | 0.65 |
| 1 | A2 | A | 1388 | --- | --- | --- | --- | 58.1 | 72.2 | C2'endo | 0.0 |
| 1 | A2 | G | 1445 | --- | --- | --- | --- | 334.8 | 340.4 | C2'endo | 0.0 |
| 1 | A2 | A | 1516 | --- | --- | --- | --- | 326.6 | 305.9 | C2'endo | 0.0 |
| 1 | A2 | U | 1522 | --- | --- | --- | --- | 2.3 | 94.4 | C2'endo | 0.043 |
| 1 | A2 | U | 1761 | --- | --- | --- | --- | 317.5 | 168.0 | C2'endo | 0.0 |
| 1 | A1 | G | 120 | --- | --- | --- | --- | 320.8 | 91.9 | C2'endo | 0.632 |
| 1 | A1 | A | 122 | --- | --- | --- | --- | 98.8 | 68.2 | C2'endo | 0.0 |
| 1 | A1 | U | 210 | --- | --- | --- | --- | 332.2 | 292.0 | C2'endo | 0.0 |
| 1 | A1 | G | 212 | 90.7 | 50.2 | --- | --- | 160.6 | 20.9 | C2'endo | 0.557 |
| 1 | A1 | G | 297 | --- | --- | --- | --- | 285.9 | 22.2 | C2'endo | 0.596 |
| 1 | A1 | U | 520 | --- | --- | --- | --- | 319.7 | 72.4 | C2'endo | 0.0 |
| 1 | A1 | C | 636 | --- | --- | --- | --- | 313.0 | 216.4 | C2'endo | 0.0 |
| 1 | A1 | A | 720 | --- | --- | --- | --- | 51.2 | 141.1 | C2'endo | 0.0 |
| 1 | A1 | A | 933 | --- | --- | --- | --- | 6.9 | 194.0 | C2'endo | 0.258 |
| 1 | A1 | U | 1096 | --- | --- | --- | --- | 317.0 | 87.8 | C2'endo | 0.0 |
| 1 | A1 | G | 1177 | --- | --- | --- | --- | 81.9 | 150.2 | C2'endo | 0.388 |
| 1 | A1 | U | 1235 | --- | --- | --- | --- | 79.1 | 110.0 | C2'endo | 0.774 |
| 1 | A1 | A | 1244 | --- | --- | --- | --- | 96.7 | 68.4 | C2'endo | 0.01 |
| 1 | A1 | G | 1268 | --- | --- | --- | --- | 301.8 | 242.0 | C2'endo | 0.494 |
| 1 | A1 | A | 1589 | 78.9 | 218.7 | --- | --- | 150.3 | 277.4 | C2'endo | 0.0 |
| 1 | A1 | G | 1906 | --- | --- | --- | --- | 327.9 | 88.5 | C2'endo | 0.0 |
| 1 | A1 | A | 2138 | --- | --- | --- | --- | 271.7 | 267.8 | C2'endo | 0.223 |
| 1 | A1 | A | 2243 | --- | --- | --- | --- | 247.4 | 18.6 | C2'endo | 0.212 |
| 1 | A1 | C | 2306 | --- | --- | --- | --- | 93.7 | 22.3 | C2'endo | 0.073 |
| 1 | A1 | A | 2402 | 334.1 | 49.4 | --- | --- | 345.5 | 125.0 | C2'endo | 0.0 |
| 1 | A1 | U | 2434 | --- | --- | --- | --- | 69.3 | 119.9 | C2'endo | 0.778 |
| 1 | A1 | U | 2541 | --- | --- | --- | --- | 91.2 | 129.0 | C2'endo | 0.0 |
| 1 | A1 | U | 2553 | --- | --- | --- | --- | 284.5 | 277.1 | C2'endo | 0.0 |
| 1 | A1 | G | 2618 | --- | --- | --- | --- | 291.1 | 269.8 | C2'endo | 0.266 |
| 1 | A1 | A | 2695 | --- | --- | --- | --- | 264.3 | 246.4 | C2'endo | 0.199 |
| 1 | A1 | A | 2808 | --- | --- | --- | --- | 101.6 | 36.3 | C2'endo | 0.084 |
| 1 | A1 | U | 3185 | --- | --- | --- | --- | 269.3 | 231.2 | C2'endo | 0.0 |
| 1 | A1 | G | 3276 | --- | --- | --- | --- | 321.6 | 207.4 | C2'endo | 0.0 |
| 1 | A1 | U | 3277 | --- | --- | --- | --- | 273.6 | 7.4 | C2'endo | 0.056 |
| 1 | A3 | U | 86 | --- | --- | --- | --- | 334.8 | 69.9 | C2'endo | 0.163 |
| 1 | A6 | A | 46 | --- | --- | --- | --- | 81.8 | 114.8 | C2'endo | 0.18 |
| 1 | A6 | A | 140 | 2.8 | 61.3 | --- | --- | 292.4 | 45.2 | C2'endo | 0.0 |
| 1 | A6 | U | 159 | --- | --- | --- | --- | 44.4 | 164.2 | C2'endo | 0.0 |
| 1 | A6 | G | 199 | --- | --- | --- | --- | 275.8 | 254.1 | C2'endo | 0.0 |
| 1 | A6 | U | 240 | 254.9 | 264.8 | --- | --- | 266.4 | 248.4 | C2'endo | 0.0 |
| 1 | A6 | U | 249 | --- | --- | --- | --- | 39.7 | 25.7 | C2'endo | 0.0 |
| 1 | A6 | U | 313 | --- | --- | --- | --- | 347.3 | 332.3 | C2'endo | 0.086 |
| 1 | A6 | G | 459 | --- | --- | --- | --- | 280.9 | 34.1 | C2'endo | 0.253 |
| 1 | A6 | A | 580 | 270.2 | 286.5 | --- | --- | 313.2 | 185.2 | C2'endo | 0.0 |
| 1 | A6 | A | 606 | --- | --- | --- | --- | 94.1 | 60.9 | C2'endo | 0.066 |
| 1 | A6 | U | 680 | --- | --- | --- | --- | 301.4 | 274.8 | C2'endo | 0.0 |
| 1 | A6 | U | 959 | 36.8 | 206.4 | --- | --- | 350.2 | 77.7 | C2'endo | 0.0 |
| 1 | A6 | U | 1060 | --- | --- | --- | --- | 88.0 | 75.0 | C2'endo | 0.0 |
| 1 | A6 | U | 1185 | --- | --- | --- | --- | 288.8 | 258.7 | C2'endo | 0.0 |
| 1 | A6 | G | 1243 | 44.3 | 66.1 | --- | --- | 0.9 | 19.6 | C2'endo | 0.0 |
| 1 | A6 | G | 1245 | --- | --- | --- | --- | 298.3 | 41.7 | C2'endo | 0.0 |
| 1 | A6 | A | 1388 | --- | --- | --- | --- | 58.7 | 73.3 | C2'endo | 0.038 |
| 1 | A6 | G | 1445 | --- | --- | --- | --- | 339.4 | 325.9 | C2'endo | 0.0 |
| 1 | A6 | A | 1516 | --- | --- | --- | --- | 327.4 | 303.7 | C2'endo | 0.0 |
| 1 | A6 | U | 1522 | --- | --- | --- | --- | 6.6 | 98.6 | C2'endo | 0.129 |
| 1 | A6 | C | 1796 | --- | --- | --- | --- | 311.6 | 330.9 | C2'endo | 0.0 |
| 1 | A5 | G | 120 | --- | --- | --- | --- | 325.2 | 89.3 | C2'endo | 0.195 |
| 1 | A5 | A | 122 | --- | --- | --- | --- | 91.7 | 71.7 | C2'endo | 0.0 |
| 1 | A5 | U | 210 | --- | --- | --- | --- | 334.5 | 293.2 | C2'endo | 0.0 |
| 1 | A5 | G | 212 | 90.4 | 48.0 | --- | --- | 161.5 | 22.2 | C2'endo | 0.579 |
| 1 | A5 | U | 520 | --- | --- | --- | --- | 319.0 | 74.2 | C2'endo | 0.0 |
| 1 | A5 | C | 636 | --- | --- | --- | --- | 313.6 | 215.5 | C2'endo | 0.0 |
| 1 | A5 | A | 720 | --- | --- | --- | --- | 57.1 | 143.1 | C2'endo | 0.0 |
| 1 | A5 | A | 1027 | 116.7 | 9.5 | --- | --- | 313.3 | 190.7 | C2'endo | 0.0 |
| 1 | A5 | U | 1096 | --- | --- | --- | --- | 315.3 | 87.8 | C2'endo | 0.0 |
| 1 | A5 | G | 1177 | --- | --- | --- | --- | 78.1 | 150.2 | C2'endo | 0.515 |
| 1 | A5 | A | 1589 | --- | --- | --- | --- | 146.5 | 276.5 | C2'endo | 0.0 |
| 1 | A5 | G | 1906 | --- | --- | --- | --- | 327.0 | 89.1 | C2'endo | 0.0 |
| 1 | A5 | A | 2138 | --- | --- | --- | --- | 271.3 | 266.6 | C2'endo | 0.496 |
| 1 | A5 | U | 2159 | --- | --- | --- | --- | 337.6 | 6.6 | C2'endo | 0.825 |
| 1 | A5 | A | 2243 | --- | --- | --- | --- | 256.6 | 20.1 | C2'endo | 0.017 |
| 1 | A5 | U | 2269 | 71.8 | 208.5 | --- | --- | 48.3 | 137.3 | C2'endo | 0.261 |
| 1 | A5 | A | 2402 | 326.4 | 39.7 | --- | --- | 66.6 | 124.0 | C2'endo | 0.0 |
| 1 | A5 | U | 2434 | --- | --- | --- | --- | 73.4 | 118.5 | C2'endo | 0.775 |
| 1 | A5 | A | 2523 | 333.2 | 237.6 | --- | --- | 312.1 | 294.3 | C2'endo | 0.0 |
| 1 | A5 | U | 2553 | --- | --- | --- | --- | 285.1 | 265.5 | C2'endo | 0.056 |
| 1 | A5 | U | 2617 | --- | --- | --- | --- | 297.1 | 244.8 | C2'endo | 0.42 |
| 1 | A5 | A | 2695 | --- | --- | --- | --- | 259.0 | 247.0 | C2'endo | 0.302 |
| 1 | A5 | A | 2808 | --- | --- | --- | --- | 61.2 | 38.3 | C2'endo | 0.083 |
| 1 | A5 | U | 2954 | --- | --- | --- | --- | 45.0 | 183.9 | C2'endo | 0.0 |
| 1 | A5 | U | 3155 | --- | --- | --- | --- | 25.9 | 206.5 | C2'endo | 0.0 |
| 1 | A5 | U | 3185 | --- | --- | --- | --- | 277.1 | 240.6 | C2'endo | 0.024 |
| 1 | A5 | U | 3319 | --- | --- | --- | --- | 14.5 | 8.4 | C2'endo | 0.0 |
| 1 | A5 | G | 3353 | --- | --- | --- | --- | 160.1 | 20.9 | C2'endo | 0.24 |
| 1 | A7 | U | 86 | --- | --- | --- | --- | 335.5 | 69.6 | C2'endo | 0.575 |